J Liver Cancer Search


Journal of the Korean Liver Cancer Study 2009;9(1):53-58.
Published online June 30, 2009.
Treatment of Massive Hepatocellular Carcinoma with Portal Vein Invasion
Jung Hyun Kwon1, Jong Young Choi1, Jin Dong Kim1, Hyun Young Woo1, Si Hyun Bae1, Seung Kew Yoon1, Young Jun Lee2, Ho Jong Chun2
1Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea
2Department of Radiology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Correspondence:  Jong Young Choi,
Email: ychoi@catholic.ac.kr
Copyright ©2009 by The Korean Liver Cancer Association
A 52 year-old-man patient was admitted for evaluation of hepatic mass which was detected on screening ultrasonography. His abdominal CT showed a massive infiltrating mass in left hepatic lobe and another 2.4 cm nodule in S6 of Rt. Hepatic lobe with arterial enhancement and rapid wash out underlying liver cirrhosis. Also, low density tumor thrombus are filled in Lt. portal vein and extended into main portal vein. He was finally diagnosed HCC (UICC stage IVa) with liver cirrhosis (Child-Pugh class A) and hepatitis B. With the four times of trasnarterial chemo-lipiodolization and seven times of intraarterial infusion chemotherapy for huge mass and one time Radiofrequency ablation (RFA) for daughter nodule, his HCC showed no stain in hepatic angiogram at nine month from initial diagnosis. After additional eight times of intra-arterial infusion chemotherapy, new small nodule developed in S6 and was ablated with RFA. At eighteen months after initial diagnosis, he shows no viable lesion on the imaging study and tumor markers are normalized.
Key Words: Massive hepatocellular carcinoma; Transarterial chemo-lipiodolization; Intra-arterial infusion chemotherapy

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