Journal of Liver Cancer

2 "Massive hepatocellular carcinoma"

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Case Reports

Treatment of Massive Hepatocellular Carcinoma with Portal Vein Invasion: Jung Hyun Kwon, Jong Young Choi, Jin Dong Kim, Hyun Young Woo, Si Hyun Bae, Seung Kew Yoon, Young Jun Lee, Ho Jong Chun; Journal of the Korean Liver Cancer Study Group. 2009;9(1):53-58. Published online June 30, 2009

Abstract PDF: A 52 year-old-man patient was admitted for evaluation of hepatic mass which was detected on screening ultrasonography. His abdominal CT showed a massive infiltrating mass in left hepatic lobe and another 2.4 cm nodule in S6 of Rt. Hepatic lobe with arterial enhancement and rapid wash out underlying liver cirrhosis. Also, low density tumor thrombus are filled in Lt. portal vein and extended into main portal vein. He was finally diagnosed HCC (UICC stage IVa) with liver cirrhosis (Child-Pugh class A) and hepatitis B. With the four times of trasnarterial chemo-lipiodolization and seven times of intraarterial infusion chemotherapy for huge mass and one time Radiofrequency ablation (RFA) for daughter nodule, his HCC showed no stain in hepatic angiogram at nine month from initial diagnosis. After additional eight times of intra-arterial infusion chemotherapy, new small nodule developed in S6 and was ablated with RFA. At eighteen months after initial diagnosis, he shows no viable lesion on the imaging study and tumor markers are normalized.

A Case of Massive HCC Treated with Surgical Resection: Shin Young Lee, Hee Bok Chae, Dong Hee Ryu, Il Hun Bae, Rohyun Sung; Journal of the Korean Liver Cancer Study Group. 2009;9(1):59-62. Published online June 30, 2009

Abstract PDF: A 59-year-old male patient visited ER complaining of persistent pain in his right upper quadrant abdomen. He had suffered from end stage renal disease secondary to long-term hypertension and had been under the maintenance hemodialysis for 13 years. Half a month ago, he recognized a mass at his epigastric area. He did not have any history of liver disease in his lifetime. Physical exams revealed that he had a tender and hard mass on his right upper quadrant and epigastric area. Total bilirubin was 0.6 mg/dL, AST/ALT was 59/75 IU/L, and AFP was 105,740 ng/mL. Computed tomography showed the huge liver mass in the left lobe and its size was estimated about 16cm. The regional lymph node was also found in the porta hepatis area. He received complete resection of the hepatoma and was discharged. We concerned about high probability of recurrence because of the pre-operative AFP level and vascular invasion in the pathologic specimen.

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