A 62-year-old male was referred to our hospital for further evaluation and treatment due to hepatocellular carcinoma. He was performed to TACE once. Threre was no evidence of abnormal finding except HBs Ag positive. We performed four times of TACE. Another hepatic mass was found on Liver CT which was observed in delyed phase not in arterial phase, portal phase. We diagnosed hepatocellular carcinoma by sono-guided Liver biopsy and radiofrequency ablation was performed because of no response to further TACE. There wad no evidence of recurring during 3-month follow-up.