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J Liver Cancer > Volume 16(1); 2016 > Article
Journal of Liver Cancer 2016;16(1):63-66.
DOI: https://doi.org/10.17998/jlc.16.1.63    Published online March 31, 2016.
A Case of Complete Remission in Patient with Extrahepatic Metastasis after Curative Resection of Hepatocellular Carcinoma by Radiotherapy, Lung Resection and Systemic Chemotherapy
Yeong Jin Kim1, Hye won Lee1,2, Ji Hoon Lee1, Jin Sil Sung2,3, Do Young Kim1,2
1Department of Internal Medicine, Yonsei University College of Medicine
2Yonsei Liver Center, Severance Hospital
3Radiologic Oncology,Yonsei University College of Medicine
Abstract
Surgical resection is mainstay treatment of hepatocellular carcinoma (HCC). However, its prognosis is poor, because of the high incidence of HCC recurrence (cumulative 5-year HCC recurrence rate of 70-80%). The most common site of HCC recurrence is the remnant liver, and extrahepatic recurrence occurs in 6.7-13.5% of patients. Because the tumor characteristics in extrahepatic recurrence are usually multiple and aggressive, the optimal treatment modality has not yet been determined. We report a case of complete remission and long term survival over 60 months in patient with extrahepatic metastasis after curative resection of HCC by aggressive treatment, which include lung resection for lung metastasis, radiotherapy for mediastinal lymph node metastasis, and systemic chemotherapy.
Key Words: Hepatocellular carcinoma; Extrahepatic metastasis; Metastasectomy; Radiotherapy; Chemotherapy
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