| A Case of Refractory Hepatocellular Carcinoma Presented with Brain Metastasis |
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Eui Bae Kim1, Soung Won Jeong1, Jae Young Jang1, Sae Hwan Lee1, Sang Gyune Kim1, Young Seok Kim1, Hong Soo Kim1, Boo Sung Kim1, A ram Jang2 |
1Institute for Digestive Research, Departments of Internal Medicine, Soonchunhyang University Hospital, Seoul, Korea
2Departments of Radiation Oncology, Soonchunhyang University Hospital, Seoul, Korea |
Correspondence:
Soung Won Jeong,
Email: eongsw@schmc.ac.kr
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| Abstract |
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Hepatocellular carcinoma (HCC) is the sixth most common tumor worldwide and the third leading cause of tumor mortality.
The majority of tumors are diagnosed when advanced and then a 5-year survival rate of HCC is below 5%. However, recent
progress in the diagnosis and treatment of HCC has made it possible for the patient to survive longer, and as a result, distant
metastasis from HCC has increased and attracted more attention than before. HCC can be metastasized to all organs through
blood and lymphatic channel. Of the various metastatic sites, the most common site is the lungs, followed by the lymph nodes,
musculoskeletal, adrenal and omentum. Also, spleen, small bowel, large bowel and esophagus can be invloved. Brain metastasis
can be occurred rarely, and then it is regarded to oncologic emergency. We report a patient who present with brain metastasis of
progressing HCC despite of treatment. |
| Key Words:
Hepatocellular carcinoma; Brain metastasis |
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