J Liver Cancer Search


Journal of the Korean Liver Cancer Study 2009;9(1):76-81.
Published online June 30, 2009.
A Case of Hepatocellular Carcinoma in a Pregnant Patient in Twenties
Kang Kook Choi1, Young Ju Hong1, Sae Byeol Choi4, Nam Joon Yi5, Shin Hwang6, Young Nyun Park2,7, Jin Sub Choi1,7, Kyung Suk Suh5, Chae Yoon Chon3,7, Kyung Sik Kim1,7
1Department of Surgery, Yonsei University College of Medicine, Seoul, Korea
2Department of Pathology, Yonsei University College of Medicine, Seoul, Korea
3Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea
4Department of Surgery, Korea University College of Medicine, Seoul, Korea
5Department. of Surgery, Seoul National University College of Medicine, Seoul, Korea
6Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
7Yonsei Liver Cancer Study Group, Seoul, Korea
Correspondence:  Kyung Sik Kim,
Email: kskim88@yuhs.ac
Copyright ©2009 by The Korean Liver Cancer Association
Hepatocellular carcinoma (HCC) in pregnancy is very rare. The cirrhosis which is present in the majority of patients with HCC induces infertility. The diagnostic methods and treatment modalities in HCC during pregnancy are different from those of usual types of other HCC. A 26-year-old, 32th-gestational-week pregnant female was sent to our hospital because of abnormal liver function test. A 1.5cm sized mass was identified in segment 6 of liver which was compatible to AJCC stage I. She did not have any other medical history except Hepatitis B Virus carrier and the HBs Ag of her mother also was positive. At the 40th gestational week, the female baby was delivered uneventfully. And then she underwent the transarterial chemoembolization (TACE) following the Rt. Hemihepatectomy. Since she underwent a surgical resection, the tumors have been recurred in the remnant liver only. Whenever the tumors were founded, the aggressive surgical approaches were performed including 3 times of hepatic resection with TACE or TACI. She is still alive with good general condition and normal liver function for 9 years since the first diagnosis was made. Therefore an extremely rare case of hepatocellular carcinoma in pregnancy is treated successfully because of aggressive therapies.
Key Words: Hepatocellular carcinoma; Pregnancy

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