J Korean Liver Cancer Stud Search


Journal of the Korean Liver Cancer Study 2008;8(1):69-73.
Published online June 30, 2008.
A Case of Hepatocellular Carcinoma with Bile Duct Invasion
Yeon Seok Seo1, Beom Jin Park2, Yun Hwan Kim2, Soon Ho Um1
1Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea
2Department of Radiology, Korea University College of Medicine, Seoul, Korea
Correspondence:  Soon Ho Um,
Email: umsh@korea.ac.kr
Copyright ©2008 by The Korean Liver Cancer Association
Cholestatic type hepatocellular carcinoma (HCC), in which obstructive jaundice is presented as the initial presentation of HCC, is rare. The prognosis of cholestatic type HCC is generally poor and most of the patients die from cholangitis or sepsis. Although some authors reported cases of successfully treated cholestatic type HCC with surgical resection, most of the patients are inoperable at the time of diagnosis. Several reports suggested that transarterial chemoembolization (TACE) showed a beneficial effect in improving the survival time and therefore, TACE should be tried as a first choice of therapy in patients with cholestatic HCC with sufficient liver reserve function. We experienced a case of obstructive jaundice as the initial presentation of HCC. His obstructive jaundice showed significant improvement after several sessions of TACE.
Key Words: Hepatocellular carcinoma; Bile duct invasion; Jaundice; Cholestasis


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