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THE KOREAN LIVER CANCER ASSOCIATION
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- Case Report A Case of Hepatoid Adenocarcinoma with High Serum Alpha-Fetoprotein Mimicking Hepatocellular Carcinoma
- Yuri Cho, Yoon Jun Kim
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Journal of Liver Cancer 2014;14(1):37-40
DOI: https://doi.org/10.17998/jlc.14.1.37
Published online: March 31, 2014
Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea
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Abstract
Hepatoid adenocarcinoma is a type of cancer with both adenocarcinomatous and hepatocellular differentiation. Hepatoid adenocarcinoma has a typical character of high serum alpha-fetoprotein (AFP) level. A 61-year-old female patient was admitted to the hospital with abdominal pain and hepatic mass. Abdominal ultrasonography revealed a 20 cm sized mass in liver. A huge hepatic mass looked like primary hepatocellular carcinoma (HCC) on liver CT and MRI. Also, serum AFP was elevated to 24215.7 ng/mL. Right trisectionectomy was done under the impression of HCC. However, the result of pathological findings including immunohistochemical staining revealed that it was a hepatoid adenocarcinoma which was originated from gallbladder
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