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HOME > J Liver Cancer > Volume 11(1); 2011 > Article
Case Report A Case of Advanced Hepatocellular Carcinoma Treated with Curative Surgical Resection after Downstaging by Hepatic Arterial Infusion Chemotherapy
Jong Ryul Eun1, Heon Ju Lee1, Jae Woon Kim2, Jay Chun Chang2, Sung Su Yun3, Joon Hyuk Choi4
Journal of Liver Cancer 2011;11(1):60-64
DOI: https://doi.org/
Published online: February 28, 2011
1Departments of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea
2Departments of Radiology, Yeungnam University College of Medicine, Daegu, Korea
3Departments of Surgery, Yeungnam University College of Medicine, Daegu, Korea
4Departments of Pathology, Yeungnam University College of Medicine, Daegu, Korea
Corresponding author:  Jong Ryul Eun,
Email: dreun@ynu.ac.kr
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Cure by single modality for advanced hepatocellular carcinoma (HCC) is difficult. Therefore, multidisciplinary approaches are needed to get a better outcome for advanced HCC. In this paper, we report a case of advanced HCC treated with curative surgical resection after downstaging by hepatic arterial infusion chemotherapy (HAIC). A 50-year-old male patient had a maximum 16.0 cm sized HCC in the right lobe. He achieved a partial response after 2 cycles of HAIC with 5-FU (750 mg/m2) and cisplatin (25 mg/m2). After completion of 6 cycles, he received a curative right hepatectomy and the histopathology revealed 95% of tumor necrosis. He is under follow-up without recurrence at 14 months of surgery. This case suggests that surgery after downstaging by HAIC may provide good clinical outcome in advanced HCC.


JLC : Journal of Liver Cancer