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Journal of the Korean Liver Cancer Study Group 2001;1(1):107-109.
Published online June 30, 2001.
A Case of Advanced Hepatocellular Carcinoma with Inferior Vena Cava and Right Atrium Invasion Treated with Intra-arterial Chemotherapy
Kee Myung Lee1, Je Han Won2, Deok Kee Kim1, Jae Geun Kim2, Won Seok Kim1, Kwang Hyeon Ko1, Sung Won Cho1
1Department of Gastroenterology, Ajou University College of Medicine
2Department of Diagnostic Radiology, Ajou University College of Medicine
Correspondence:  Kee Myung Lee,
Email: gikang20@chollian.net
Abstract
A 52 year-old-male patient was admitted to our hospital due to hematemesis. Ten years ago, he had been diagnosed chronic hepatitis B and he was heavy alcoholics. He was in the state of SB tube insertion and we had esophagogastroduodenoscopy and found out cardiac varix bleeding and injected history1. On abdominal ultrasonograpy, large hypoechoic mass in left lobe of liver was noted and the mass invaded into hepatic vein, inferior vena cava (IVC), and right atrium. On hepatic arteriography, large hypervascular mass in left lobe of the liver and several small dodules in right lobe were noted. We performed chemoembolization to the nodules in right lobe but cannot performed to the lesion in left love due to arteriovenous shunt. We inserted the chemport catheter to proper hepatic artery and started the intra-arterial chemotherapy (IACT) with 5-FU 250 mg and cisplatin 10 mg for 5 days. After the second cycle of IACT, tumor thrombus in right atrium was disappeared and thrombus in IVC and tumor mass in left lobe were decreased in size. We believed that hepatocellular carcinoma of this patient should be sensitive to chemotherapy and planned the additional IACT treatment.
Key Words: Intra-arterial chemotherapy; Hepatocellular carcinoma with inferior vena cava and right atrium involvment
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