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Journal of the Korean Liver Cancer Study 2011;11(2):190-194.
Published online September 30, 2011.
A Case of Aggressive Treatment with Transarterial Embolization Using Drug-Eluting Beads for Hepatocellular Carcinoma in Decompensated Liver Cirrhosis Patient
Eileen L. Yoon1, Hyung Joon Yim1, Hwan Hoon Chung2, Seung Hwa Lee2, Hae Rim Kim1, Jong Jin Hyun1, Sung Woo Jung1, Ja Seol Koo1, Sang Woo Lee1, Jai Hyun Choi1
1Departments of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine, Seoul, Korea
2Departments of Radiology, Korea University Ansan Hospital, Korea University College of Medicine, Seoul, Korea
Correspondence:  Hyung Joon Yim,
Email: gudwns21@medimail.co.kr
Copyright ©2011 by The Korean Liver Cancer Association
Abstract
Conventional transarterical chemoembolization (TACE) is the first-line treatment for patients with intermediate stage of hepatocellular carcinoma (HCC). However, irreversible liver failure after the procedure is one of the most feared complications and therefore, decompensated Child-Pugh C patients may not be the indication of the conventional TACE. Drug-eluting beads loaded with doxorubicin is a novel drug delivery embolization system and reported to have non inferior efficacy compared to conventional TACE. Also drug-eluting beads loaded with doxorubicin is associated with lower rates of acute liver failure after the procedure and lower rates of systemic toxicity of the chemotherapeutic agents. Herein, we report a case of aggressive treatment with transarterial embolization using drug-eluting beads loaded with doxorubicin for HCC in decompensated liver cirrhosis patient who was not eligible for conventional TACE treatment.
Key Words: Drug-eluting beads; Hepatic decompensation; Hepatocellular carcinoma
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