A Case of Aggressive Treatment with Transarterial Embolization Using Drug-Eluting Beads for Hepatocellular Carcinoma in Decompensated Liver Cirrhosis Patient |
Eileen L. Yoon1, Hyung Joon Yim1, Hwan Hoon Chung2, Seung Hwa Lee2, Hae Rim Kim1, Jong Jin Hyun1, Sung Woo Jung1, Ja Seol Koo1, Sang Woo Lee1, Jai Hyun Choi1 |
1Departments of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine, Seoul, Korea 2Departments of Radiology, Korea University Ansan Hospital, Korea University College of Medicine, Seoul, Korea |
Correspondence:
Hyung Joon Yim, Email: gudwns21@medimail.co.kr |
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Abstract |
Conventional transarterical chemoembolization (TACE) is the first-line treatment for patients with intermediate stage of
hepatocellular carcinoma (HCC). However, irreversible liver failure after the procedure is one of the most feared complications
and therefore, decompensated Child-Pugh C patients may not be the indication of the conventional TACE. Drug-eluting beads
loaded with doxorubicin is a novel drug delivery embolization system and reported to have non inferior efficacy compared to
conventional TACE. Also drug-eluting beads loaded with doxorubicin is associated with lower rates of acute liver failure after
the procedure and lower rates of systemic toxicity of the chemotherapeutic agents. Herein, we report a case of aggressive
treatment with transarterial embolization using drug-eluting beads loaded with doxorubicin for HCC in decompensated liver
cirrhosis patient who was not eligible for conventional TACE treatment. |
Key Words:
Drug-eluting beads; Hepatic decompensation; Hepatocellular carcinoma |
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