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HOME > J Liver Cancer > Volume 10(1); 2010 > Article
Case Report A Case of Hepatocellular Carcinoma Exhibited over Partial Response after Hepatic Arterial Infusion Chemotherapy
Chang Wook Park1, Young Lan Kown1, Yong Jin Kim1, Yoon Jung Kim1, Hye Jin Seo1, Kyung In Lee1, Eun Soo Kim1, Byung Kook Jang1, Woo Jin Jeong1, Kyung Sik Park1, Kwang Bum Jo1, Jae Seok Hwang1, Young Hwan Kim2, Jung Hyuk Kwon2
Journal of Liver Cancer 2010;10(1):40-43
DOI: https://doi.org/
Published online: June 30, 2010
1Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea
2Department of Radiology, Keimyung University School of Medicine, Daegu, Korea
Corresponding author:  Jae Seok Hwang,
Email: gastro@dsmc.or.kr
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Hepatocellular carcinoma (HCC) is one of the cancers with poor prognosis. Especially potal vein invasion is a grave prognostic indicator in the setting of HCC. There is currently no effective method for treatment of HCC with portal vein invasion. A 61-year-old female patient was diagnosed a massive HCCs in both hepatic lobe with portal vein thrombosis, based on computed tomography (CT) and increased tumor marker, α-fetoprotein. She was treated with intrahepatic arterial CDDP (10 mg on 1~5 day), 5-FU (250mg on 1~5 day) and leukovorin (12mg on 1~5 day) infusion via percutaneously implantable port system (PIPS) every 3 weeks, totally seven times. The patient was still living 6 months after first hepatic arterial infusion chemotherapy (HAIC) and follow-up CT showed partial response with necrosis of HCCs. We report here a case of advanced HCC with portal vein thrombosis that was effectively treated with HAIC via PIPS.

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