J Liver Cancer Search


Journal of the Korean Liver Cancer Study Group 2009;9(1):63-66.
Published online June 30, 2009.
A Case of Massive Hepatocellular Carcinoma Treated by Hepatic Resection, which did not Respond to Transarterial Chemoembolization
Jeong Han Kim1, Hyung Joon Yim1, Seung Young Kim1, Jae Hong Ahn1, Ji Hoon Kim1, Yeon Seok Seo1, Seung Hwa Lee2, Hwan Hoon Chung2, Tae Jin Song3, Hong Sik Lee1, Sang Woo Lee1, Jai Hyun Choi1
1Departments of Internal Medicine, Korea University College of Medicine, Seoul, Korea
2 Departments of Radiology, Korea University College of Medicine, Seoul, Korea
3Departments of Surgery, Korea University College of Medicine, Seoul, Korea
Correspondence:  Hyung Joon Yim,
Email: gudwns21@medimail.co.kr
Surgical resection is the treatment of choice for hepatocellular carcinoma (HCC) in non-cirrhotic patients. The optimal indication for resection is a single tumor in a suitable location for resection. However, limit of the tumor size is not clear. We report a case of successful hepatic resection in patients with massive HCC sized more than 15 cm that did not respond to transarterial chemoembolization (TACE). A 49-year-old male patient had received TACE two times for massive HCC. However, the tumor size increased. Right hemihepatectomy was performed despite the extensive tumor size and underlying liver cirrhosis. Ascites and wound infection were developed after resection, but the patient’s general condition got recovered soon. Until 6 months after surgery, recurrence has not been detected. However, distant metastasis was noted at 7th month. Although recurrence with distant metastasis was noted, we think aggressive surgical approach prolonged this patient’s survival.
Key Words: Hepatocellular carcinoma; Transarterial chemoembolization; Hepatic resection

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