Focal nodular hyperplasia (FNH) of the liver is a rare benign lesion characterized by nodular hyperplasia of hepatic parenchyma around a central stellate area of fibrosis associated with an anomalous artery. The histological feature of FNH is dominated by a progressive fibrotic process. In the present report, we described a 2.2×2.1 cm sized asymptomatic lesion of FNH observed in a 47-year-old woman with hepatitis B healthy carrier. This lesion was disclosed by various imaging procedures. Under the clinical impression of hepatocellular carcinoma a right. lobe subsegmentectomy was performed. The mass was firm and showed yellow-brownish color and septal fibrosis. It was accompanied with marginal ductal proliferation. These results were consistent with the typical observations in FNH. It also showed small stellate scar with radiating thin fibrous band and formation of small parenchymal nodules. We report a case of FNH of the liver difficult to differentiate hepatocellular carcinoma.