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- Case Report A Case of Positive Tumor Marker Response after Intra-arterial Deferoxamine Infusion Therapy in a Hepatocellular Carcinoma Patient with Decompensated Liver Function
- Hyun Ju Kim1, Wonseok Kang1, Mi Na Kim1,2, Beom Kyung Kim1,2,3, Seung Up Kim1,2,3, Do Young Kim1,2,3, Sang Hoon Ahn1,2,3, Kwang-Hyub Han1,2,3
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Journal of Liver Cancer 2014;14(2):127-130
DOI: https://doi.org/10.17998/jlc.14.2.127
Published online: September 30, 2014
2Institute of Gastroenterology, Yonsei University College of Medicine
3Liver Cirrhosis Clinical Research Center, Yonsei University College of Medicine
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Corresponding author:
Kwang-Hyub Han,
Email: gihankhys@yuhs.ac.kr
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Abstract
Treatment of hepatocellular carcinoma is often very challenging when the underlying liver function is decompensated. Recent experimental and clinical studies showed that some chelating agents, including deferoxamine, display anti-proliferative actions against tumor cells, thereby exhibiting anti-cancer effect in certain cancers, including hepatocellular carcinoma. Based on previous studies, we herein offer our experience of positive tumor marker response after intra-arterial deferoxamine infusion in a patient presenting with advanced hepatocellular carcinoma with decompensated hepatic function. Validation of the efficacy of intra-arterial deferoxamine therapy in the setting of advanced hepatocellular carcinoma with underlying decompensated hepatic function is warranted. (J Liver Cancer 2014;14:127-130)
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