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HOME > J Liver Cancer > Volume 3(1); 2003 > Article
Case Report Hypovascular Hepatocellular Carcinoma Supposed to Originate from Dysplastic Nodule
Nam Young Jo1, Soon Ho Um1, Kum Won Kim2, Yun Hwan Kim2, Nam Hee Won3
Journal of Liver Cancer 2003;3(1):87-91
DOI: https://doi.org/
Published online: July 31, 2003
1Department of Internal Medicine, Korea University College of Medicine
2Department of Diagnostic Radiology, Korea University College of Medicine
3Department of Pathology,Korea University College of Medicine
Corresponding author:  Soon Ho Um,
Email: kumcge@chollian.net
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Hepatocellular carcinoma (HCC) typically shows hepatic arterial phase contrast-enhancement and wash out pattern at portal phase. Hepatic dysplastic nodules show diverse imaging characteristics but commonly show hypoattenuation pattern at CT-imaging. We report an 3 cm sized atypical hypovascular HCC which was thought to orginate from dysplastic nodule. Fifty senven year old female who had suffered from chronic hepatitis B had three separate hepatic nodules initially. One in seg 7 diagnosed as well-differentiated HCC, another in seg 5 as dysplastic nodule by US guided needle biopsy. Remaining 1.5 cm sized nodule in seg 4 which showed isoattenuation at arterial phase and hypoattenuation at portal phase. We avoid invasive treatment to seg 4 nodule due to vicinity of great vessel. We performed transarterial chemoembolization (TACE) and percutaneous ethanol injection to the seg 7 & seg 5 lesions and followed up with TACE. At 2 years later the nodule in seg 4 grew up to 3 cm sized mass with showed persistency no arterial phase enhancement and partially hypoattenuating-isoattenuating pattern at portal phase. The mass diagnosed as clear cell type HCC (Edmoson grade Ⅱ) by US guided biopsy.

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