J Liver Cancer Search


Journal of the Korean Liver Cancer Study Group 2002;2(1):105-108.
Published online July 31, 2002.
A Case of Early Hepatocellular Carcinoma with High Grade Dysplastic Nodule
Jae Young Jang 1, Yun Soo Kim1, Young Kuk Cheon1, Young Seok Kim1, Jong Ho Moon1, Young Deok Cho1, So Young Jin2, Chan Sup Shim1, Boo Seong Kim1
1Department of Internal Medicine, Institute for Digestive Disease, SoonChunHyang University College of Medicine
2Department of Pathology, SoonChunHyang University College of Medicine
Correspondence:  Yun Soo Kim,
Email: kimyssch@hotmail.com
A 47-year-old male was referred for evaluation of a hepatic nodular lesion incidentally found on routine check up. He had no history of previous liver disease. Physical examination revealed no abonormality. Laboratory findings showed that HBsAG and anti-HCV were negative. Serum AST was minimally elevated and serum AFP was within normal range. Abdominal ultrasonogram showed a 1.3 cm-sized, hypoechoic nodule with peripheral halo in segment 5 of liver. Spiral CT revealed a well enhancing nodule in arterial phase, which could not be detected in portal and delayed phase. Liver biopsy showed well-differenciated hepatocellular carcinoma on the background of high grade dysplastic nodule. Surgical resection was recommended, however he refused and discharged.
Key Words: Early hepatocellular carcinoma; High grade dysplastic nodule

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