A Case of Early Hepatocellular Carcinoma with High Grade Dysplastic Nodule

Jang , Jae Young; Kim, Yun Soo; Cheon, Young Kuk; Kim, Young Seok; Moon, Jong Ho; Cho, Young Deok; Jin, So Young; Shim, Chan Sup; Kim, Boo Seong

Case Report

Journal of the Korean Liver Cancer Study 2002;2(1):105-108.
Published online July 31, 2002.

A Case of Early Hepatocellular Carcinoma with High Grade Dysplastic Nodule

Jae Young Jang ¹, Yun Soo Kim¹, Young Kuk Cheon¹, Young Seok Kim¹, Jong Ho Moon¹, Young Deok Cho¹, So Young Jin², Chan Sup Shim¹, Boo Seong Kim¹

¹Department of Internal Medicine, Institute for Digestive Disease, SoonChunHyang University College of Medicine
²Department of Pathology, SoonChunHyang University College of Medicine

Correspondence: Yun Soo Kim,
Email: kimyssch@hotmail.com

Abstract

A 47-year-old male was referred for evaluation of a hepatic nodular lesion incidentally found on routine check up. He had no history of previous liver disease. Physical examination revealed no abonormality. Laboratory findings showed that HBsAG and anti-HCV were negative. Serum AST was minimally elevated and serum AFP was within normal range. Abdominal ultrasonogram showed a 1.3 cm-sized, hypoechoic nodule with peripheral halo in segment 5 of liver. Spiral CT revealed a well enhancing nodule in arterial phase, which could not be detected in portal and delayed phase. Liver biopsy showed well-differenciated hepatocellular carcinoma on the background of high grade dysplastic nodule. Surgical resection was recommended, however he refused and discharged.

Key Words: Early hepatocellular carcinoma; High grade dysplastic nodule

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