Hepatocellular Carcinoma Arising in Hepatic Adenomatosis

Lee, Sun-Young; Choi, Moon Seok; Lee, Joon Hyoek; Koh, Kwang Cheol; Paik, Seung Woon; Lee, Won Jae

Case Report

Journal of the Korean Liver Cancer Study 2002;2(1):80-82.
Published online July 31, 2002.

Hepatocellular Carcinoma Arising in Hepatic Adenomatosis

Sun-Young Lee¹, Moon Seok Choi¹, Joon Hyoek Lee¹, Kwang Cheol Koh¹, Seung Woon Paik¹, Won Jae Lee²

¹Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine
²Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine

Correspondence: Kwang Cheol Koh,
Email: kckoh@smc.samgsung.co.kr

Abstract

Hepatic adenomatosis is a disease entity composed of more than 10 adenomas within a normal liver parenchyme. Adenomas in hepatic adenomatosis impare liver function such as ALP and GGT, and also increase the risk of carcinoma and hemorrhage. Imaging study plays important role in diagnosis. And although there is a high risk of hemorrhage via biopsy, it is important to confirm the malignant component and differentiate from metastatic disease or multifocal hepatocellular carcinoma. The treatment is usually lobectomy or embolization of the arterial supply to the largest tumor. A 28 year-old-man visited our mstitute because of abnormal findings in routine liver function test. On CT finding, there were 15 hepatic masses. The largest one was exceeding 9 cm locating in the right lobe. Although the largest mass revealed hepatocellular carcinoma through biopsy, other 14 nodules were all adenomas. Right lobectomy was done. After 2 months from the operation, transarterial chemoembolization was done for the two times thereafter. He is on regular follow-up at outpatient department without evidence of recurrence.

Key Words: Hepatic adenomatosis; Hepatocellular carcinoma; Lobectomy; Transarterial chemoembolization

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