J Liver Cancer Search


J Liver Cancer > Volume 16(2); 2016 > Article
Journal of Liver Cancer 2016;16(2):145-150.
DOI: https://doi.org/10.17998/jlc.16.2.145    Published online September 30, 2016.
A Case of Surgical Resection in Hepatocellular Carcinoma with Pulmonary Metastasis
Woo Jin Jung1, Jae Young Jang1, Jun Seok Park1, Hee Jeong Lee1, Young Kyu Cho1, Soung Won Jeong1, Sae Hwan Lee2, Snag Gyune Kim3, Sang Woo Cha1, Young Seok Kim3, Young Deok Cho1, Hong Soo Kim2, Boo Sung Kim1
1Department of Internal Medicine, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Korea
2Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine,Cheonan, Korea
3Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine,Bucheon, Korea
Correspondence:  Jae Young Jang,
Email: jyjang@schmc.ac.kr
Hepatocellular carcinoma (HCC) is well known malignancy with poor prognosis, even after resection of the primary tumor. Sorafenib is the first-line treatment in advanced HCC, but the disease control rate of sorafenib is only 43%. Pulmonary metastasectomy in patients with pulmonary metastasis from HCC has been reported to increase long-term survival compared with systemic chemotherapy. Video-assisted thoracic surgery is considered a reliable approach to the diagnosis and treatment of pulmonary diseases with low complication rate. Pulmonary metastasectomy is not universally accepted because of frequent local recurrence, an uncontrollable primary tumor, and frequent multiple pulmonary metastases in HCC, but outcome of pulmonary metastasectomy and adjuvant sorafenib therapy has not been studied. We experienced a patient who had advanced HCC with pulmonary oligometastasis and received surgical resection of the metastatic pulmonary nodule and sorafenib chemotherapy. In advanced HCC with pulmonary oligometastasis, surgical resection of pulmonary metastasis and sorafenib chemotherapy should be considered.
Key Words: Hepatocellular carcinoma; Metastasis; Metastasectomy; Sorafenib

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