A Case of Rapid Progressive Extrahepatic Metastasis of Hepatocellular Carcinoma after Surgical Resection for Huge Single Mass |
Eun Sun Jang1, Haeryoung Kim2, Young Rok Choi3, Jai Young Cho3, Yoo-Seok Yoon3, Ho-Seong Han3, Ji Hyun Kim1, Jin-Wook Kim1, Sook-Hyang Jeong1 |
1Dept. of Internal Medicine, Seoul Natl. Univ. Bundang Hospital, Seoul National Univ., College of Medicine, Seongnam, Korea 2Dept. of Pathology, Seoul Natl. Univ. Bundang Hospital, Seoul National Univ., College of Medicine, Seongnam, Korea 3Dept. of Surgery, Seoul Natl. Univ. Bundang Hospital, Seoul National Univ., College of Medicine, Seongnam, Korea |
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Abstract |
Hepatocellular carcinoma (HCC) shows a poor prognosis with high recurrence rate even after
surgical resection. To improve prognosis of HCC patient, regular surveillance for high-risk
group is recommended, but cost-benefit of the surveillance under 40 years old Asian male
with hepatitis B infection is unclear. We share a 39-year-old male case which showed early
recurrence and rapid extrahepatic metastasis after surgical resection for single huge HCC.
Based on the pathologic finding, this case was diagnosed with ‘stemness’-related markerexpressing
HCC. Further molecular classification for HCC could be beneficial to estimate
individual risk for HCC recurrence and to predict prognosis. |
Key Words:
Hepatocellular carcinoma; Classification; Metastasis; Prognosis |
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