A Case of Rapid Progressive Extrahepatic Metastasis of Hepatocellular Carcinoma after Surgical Resection for Huge Single Mass

Jang, Eun Sun; Kim, Haeryoung; Choi, Young Rok; Cho, Jai Young; Yoon, Yoo-Seok; Han, Ho-Seong; Kim, Ji Hyun; Kim, Jin-Wook; Jeong, Sook-Hyang

doi:2016.16.1.42

J Liver Cancer > Volume 16(1); 2016 > Article

Case Report

Journal of Liver Cancer 2016;16(1):42-46.
DOI: https://doi.org/10.17998/jlc.16.1.42 Published online March 31, 2016.

A Case of Rapid Progressive Extrahepatic Metastasis of Hepatocellular Carcinoma after Surgical Resection for Huge Single Mass

Eun Sun Jang¹, Haeryoung Kim², Young Rok Choi³, Jai Young Cho³, Yoo-Seok Yoon³, Ho-Seong Han³, Ji Hyun Kim¹, Jin-Wook Kim¹, Sook-Hyang Jeong¹

¹Dept. of Internal Medicine, Seoul Natl. Univ. Bundang Hospital, Seoul National Univ., College of Medicine, Seongnam, Korea
²Dept. of Pathology, Seoul Natl. Univ. Bundang Hospital, Seoul National Univ., College of Medicine, Seongnam, Korea
³Dept. of Surgery, Seoul Natl. Univ. Bundang Hospital, Seoul National Univ., College of Medicine, Seongnam, Korea

Abstract

Hepatocellular carcinoma (HCC) shows a poor prognosis with high recurrence rate even after surgical resection. To improve prognosis of HCC patient, regular surveillance for high-risk group is recommended, but cost-benefit of the surveillance under 40 years old Asian male with hepatitis B infection is unclear. We share a 39-year-old male case which showed early recurrence and rapid extrahepatic metastasis after surgical resection for single huge HCC. Based on the pathologic finding, this case was diagnosed with ‘stemness’-related markerexpressing HCC. Further molecular classification for HCC could be beneficial to estimate individual risk for HCC recurrence and to predict prognosis.

Key Words: Hepatocellular carcinoma; Classification; Metastasis; Prognosis

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