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J Liver Cancer > Volume 13(2); 2013 > Article
Journal of the Korean Liver Cancer Study Group 2013;13(2):158-163.
DOI: https://doi.org/10.17998/jlc.13.2.158    Published online September 30, 2013.
A Case of Hepatocellular Carcinoma with Bile Duct Invasion Treated with Transarterial Chemoembolization
Hee Yeon Kim1, Chang Wook Kim1, Chang Don Lee1, Soo Lim Lee2, Yoo Dong Won2, Ye Il Kim2
1Departments of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea
2Departments of Radiology, The Catholic University of Korea College of Medicine, Seoul, Korea
Correspondence:  Chang Wook Kim,
Email: cwkim@catholic.ac.kr
A 53-year-old female patient visited our hospital complaining of intermittent right upper quadrant pain for 6 months. Computed tomography (CT) scan revealed an irregular shaped tumor at segment 4 of the liver with biliary tumor thrombi extending into the common bile duct. Percutaneous transhepatic biliary drainage was done for decompression of bile duct dilatation. The patient underwent 6 sessions of transarterial chemoembolization (TACE). Partial response was obtained shortly after TACE. However, regrowth of intraductal tumor resulted in an obstructive jaundice. After a slight decompression of the obstructive jaundice, the patient underwent TACE. Jaundice temporarily worsened following the TACE, but improved, and follow-up CT demonstrated some shrinkage of the intraductal mass. This case indicates that obstructive-type jaundice may not be a contraindication for TACE, and aggressive TACE may improve prognoses of patients with hepatocellular carcinoma and biliary tumor thrombi.
Key Words: Hepatocellular carcinoma; Biliary Tract Neoplasms; Transarterial chemoembolization; Jaundice, obstructive; Cholestasis

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