J Liver Cancer Search


Journal of the Korean Liver Cancer Study Group 2012;12(2):141-145.
Published online September 30, 2012.
A Case of Hepatocellular Carcinoma with Tumor Thrombus in Inferior Vena Cava and Right Atrium
Hyun Jung Lee1, Hyung Joon Yim1, Hwan Hoon Chung2, Seung Hwa Lee2, Hae Rim Kim1, Jong Jin Hyun1, Sung Woo Jung1, Ja Seol Koo1, Sang Woo Lee1, Jai Hyun Choi1
1Departments of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Korea
2Departments of Radiology, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Korea
Correspondence:  Hyung Joon Yim,
Email: gudwns21@medimail.co.kr
In patients with advanced hepatocellular carcinoma (HCC), tumor thrombus in inferior vena cava (IVC) and right atrium (RA) are not uncommon findings and are usually associated with extremely poor outcome. Although aggressive surgical interventions such as extracorporeal circulation and tumor excision have been performed, the reported results were still unsatisfactory. Herein, we report the favorable result of combined treatment with radiation therapy and transarterial chemoembolization in a patient with advanced HCC with extensive tumor thrombus through the IVC into the RA. In conclusion, noninvasive combined modalities, such as transarterial chemoembolization and radiation therapy may sometimes provide effective palliation for patients with far advanced HCC with IVC/RA tumor thrombus and who are not candidates for alternative treatment options.
Key Words: Hepatocellular carcinoma; Tumor thrombus; Right atrium; Inferior vena cava

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