J Liver Cancer Search


Journal of the Korean Liver Cancer Study Group 2012;12(1):67-70.
Published online February 28, 2012.
A Case of Successful Treatment of Hepatocellular Carcinoma with a Pulmonary Metastasis by Combining Pulmonary Wedge Resection and Sorafenib
Sun Jae Lee1, Hyung Joon Yim1, Hwan Hoon Chung2, Hae Rim Kim1, Eileen L. Yoon1, Jong Jin Hyun1, Sung Woo Jung1, Ja Seol Koo1, Rok Son Choung1, Sang Woo Lee1, Jai Hyun Choi1
1Division of Gastroenterology and Hepatology, Departments of Internal Medicine, Korea University College of Medicine, Seoul, Korea
2Departments of Radiology, Korea University College of Medicine, Seoul, Korea
Correspondence:  Hyung Joon Yim,
Email: gudwns21@medimail.co.kr
35-year-old female patient was diagnosed with hepatocellular carcinoma and underwent hepatic resection. 12 months after hepatic resection, serum AFP rose (119.6 ng/mL) but no definite recurrence was found on imaging modalities. 30 months after hepatic resection, serum AFP rose up to 1008.5 ng/mL and metastatic nodule was found in right lower lung in chest CT. Video assisted thoracoscopic wedge resection was performed and 400 mg/day of sorafenib was intiated. Serum AFP returned to normal range after 2 months of pulmonary resection. No evidence of recurrence is noted after 30 months of pulmonary resection. We think that pulmonary resection plus sorafenib combination therapy resulted in favorable treatment outcome in this patient.
Key Words: Hepatocellular carcinoma; Pulmonary resection; Sorafenib

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