A One cm Sized Intrahepatic Cholangiocarcinoma in a Patient with Chronic Hepatiits B Misdiagnosed as Hepatocellular Carcinoma |
Gene Hyun Bok1, Soung Won Jeong1, Jae Young Jang1, Kwang Yeun Shim1, Sae Hwan Lee1, Sang Gyune Kim1, Young Seok Kim1, Hong Soo Kim1, Boo Sung Kim1, So Young Jin2, Sung Sook Hong3, Yong Jae Kim3 |
1Departments of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea 2Departments of Pathology, Soonchunhyang University College of Medicine, Seoul, Korea 3Departments of Radiology, Soonchunhyang University College of Medicine, Seoul, Korea |
Correspondence:
Soung Won Jeong, Email: jeongsw@schmc.ac.kr |
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Abstract |
Morphologically, intrahepatic cholangiocarcinoma (ICC) presents as a parenchymal mass, and it is occasionally resectable and
potentially curable. In some cases, differentiation from other hepatic neoplasms such as metastatic lesions and hepatocellular
carcinoma (HCC) can be extremely difficult, both clinically and histologically, and definitive diagnosis often needs correlation
with clinical and radiologic finding.Contrasted computed tomography (CT) is useful in the diagnosis of ICC and in determining
the extent of tumor involvement. Although the majority of liver tumors can be diagnosed by modern imaging modalities such as
contrast CT, some cases of ICC show tumor enhancement in the arterial phase the same as that in HCC, or a biliary dilatation
without stenosis by intraductal tumor growth. Differences in these patterns of tumor enhancement and status of the bile ducts in
ICC may also reflect differences in cellular characteristics, clinical features, and prognosis after treatment. We present a case of a
small ICC showing similar clinical and radiologic characteristics to HCC. |
Key Words:
Intrahepatic cholangiocarcinoma; Hepatocellular carcinoma; Liver nodule |
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