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Journal of the Korean Liver Cancer Study Group 2012;12(1):23-27.
Published online February 28, 2012.
A One cm Sized Intrahepatic Cholangiocarcinoma in a Patient with Chronic Hepatiits B Misdiagnosed as Hepatocellular Carcinoma
Gene Hyun Bok1, Soung Won Jeong1, Jae Young Jang1, Kwang Yeun Shim1, Sae Hwan Lee1, Sang Gyune Kim1, Young Seok Kim1, Hong Soo Kim1, Boo Sung Kim1, So Young Jin2, Sung Sook Hong3, Yong Jae Kim3
1Departments of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea
2Departments of Pathology, Soonchunhyang University College of Medicine, Seoul, Korea
3Departments of Radiology, Soonchunhyang University College of Medicine, Seoul, Korea
Correspondence:  Soung Won Jeong,
Email: jeongsw@schmc.ac.kr
Abstract
Morphologically, intrahepatic cholangiocarcinoma (ICC) presents as a parenchymal mass, and it is occasionally resectable and potentially curable. In some cases, differentiation from other hepatic neoplasms such as metastatic lesions and hepatocellular carcinoma (HCC) can be extremely difficult, both clinically and histologically, and definitive diagnosis often needs correlation with clinical and radiologic finding.Contrasted computed tomography (CT) is useful in the diagnosis of ICC and in determining the extent of tumor involvement. Although the majority of liver tumors can be diagnosed by modern imaging modalities such as contrast CT, some cases of ICC show tumor enhancement in the arterial phase the same as that in HCC, or a biliary dilatation without stenosis by intraductal tumor growth. Differences in these patterns of tumor enhancement and status of the bile ducts in ICC may also reflect differences in cellular characteristics, clinical features, and prognosis after treatment. We present a case of a small ICC showing similar clinical and radiologic characteristics to HCC.
Key Words: Intrahepatic cholangiocarcinoma; Hepatocellular carcinoma; Liver nodule
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