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Journal of the Korean Liver Cancer Study 2009;9(1):82-85.
Published online June 30, 2009.
A Case of Advanced Hepatocellular Carcinoma in Twenties Treated by Multimodality Therapy
Jang Eun Lee1, Na Ri Yoon1, Si Hyun Bae1, Jong Young Choi1, Seung Kew Yoon1, Dong Goo Kim2, Ho Jong Chun3, Byung Gil Choi3, Hae Giu Lee3, Hong Seok Jang4, Chan Kwon Jung5, Eun Sun Jang5
1Departments of Internal Medicine, Seoul St. Mary’ Hospital, The College of Catholic University, Seoul, Korea
2Departments of Surgery, Seoul St. Mary’ Hospital, The College of Catholic University, Seoul, Korea
3Departments of Radiology, Seoul St. Mary’ Hospital, The College of Catholic University, Seoul, Korea
4Departments of Radiation Oncology, Seoul St. Mary’ Hospital, The College of Catholic University, Seoul, Korea
5Departments of Hospital Pathology, Seoul St. Mary’ Hospital, The College of Catholic University, Seoul, Korea
Correspondence:  Jong Young Choi,
Email: ychoi@catholic.ac.kr
Copyright ©2009 by The Korean Liver Cancer Association
Abstract
The prognosis of young patients with hepatocellular carcinoma is remains controversial. Here we report a case of advanced hepatocellular carcinoma in twenty, successfully treated with transarterial chemolipidolization (TACL), systemic chemotherapy, radiation therapy and surgical resection. Previously healthy 28 years old woman was admitted for treatment of hepatocellular carcinoma. Abdominal CT showed a diffuse infiltrative HCC involving both lobes with intrahepatic bile duct invasion and pericardial lymphadenopathy. She was treated TAC with systemic chemotherapy and external beam radiotherapy. 6 months after these treatments, main tumor and the pericardial lymph node were decreased in size. And then extended left lobectomy and systemic chemotherapy were done. The pericardial lymph node was markedly decreased. The patient has been followed for 10 months without evidence of regional tumor recurrence.
Key Words: Hepatocellular carcinoma; Young age; Transarterial chemolipiodolization; Radiation therapy; Hepatic lobectomy
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