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Journal of the Korean Liver Cancer Study 2009;9(1):33-36.
Published online June 30, 2009.
A Case of Hepatocellular Carcinoma Presenting Early Intrahepatic Recurrence Following Hepatic Resection
Jaejun Shim2, Byung-Ho Kim2, Young Hwangbo2, Sang Wook Lee2, Young Ju Lee2, Seung Hyung Ha2, Jae Young Jang2, Seok Ho Dong2, Hyo Jong Kim2, Young Woon Chang2, Rin Chang2, Sang Mok Lee3
2Departments of Internal Medicine, Kyung Hee University School of Medicine, Seoul, Korea
3Departments of General Surgery, Kyung Hee University School of Medicine, Seoul, Korea
Correspondence:  Byung-Ho Kim,
Email: kimbh@khu.ac.kr
Copyright ©2009 by The Korean Liver Cancer Association
Abstract
Long term results of hepatic resection for hepatocellular carcinoma (HCC) are not satisfactory due to a high incidence of postoperative recurrence. To improve the prognosis in patients who underwent hepatic resection, identification of risk factors for recurrence and development of effective preventive strategies are required. A single nodular mass was found in the right hepatic lobe of 53-year old male with B viral cirrhosis by surveillance ultrasonography. Dynamic abdominal CT showed a 3 cm-sized hypervascular mass in the right posteroinferior segment (S6). AFP was 359 ng/mL. Child-Pugh classification was A, and ICG R15 was 18.8%. After preoperative transarterial chemoembolization (TACE), right hepatic wedge resection was performed. Resection margin was free of tumor. Microinvasions in the surrounding vessels, lymphatics, bile ducts were not found and microsatellite nodules were absent in the resected specimen. Although there were no risk factors that associated with high postoperative recurrence, multifocal intrahepatic recurrence in the right lobe and left medial lobe occurred at 7 months after hepatic resection. He underwent two sessions of TACE.
Key Words: Hepatocellular carcinoma; Hepatectomy; Chemoembolization, Therapeutic; Neoplasm Recurrence
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