A Case of Hepatocellular Carcinoma with Early Multiple Recurrences after Liver Resection

Ahn, Jae Hong; Yim, Hyung Joon; Kim, Seung Young; Kim, Jeong Han; Seo, Yeon Seok; Lee, Seung Hwa; Chung, Hwan Hoon; Song, Tae Jin; Lee, Hong Sik; Lee, Sang Woo; Um, Soon Ho; Choi, Jai Hyun; Ryu, Ho Sang

Case Report

Journal of the Korean Liver Cancer Study 2009;9(1):29-32.
Published online June 30, 2009.

A Case of Hepatocellular Carcinoma with Early Multiple Recurrences after Liver Resection

Jae Hong Ahn¹, Hyung Joon Yim¹, Seung Young Kim¹, Jeong Han Kim¹, Yeon Seok Seo¹, Seung Hwa Lee², Hwan Hoon Chung², Tae Jin Song³, Hong Sik Lee¹, Sang Woo Lee¹, Soon Ho Um¹, Jai Hyun Choi¹, Ho Sang Ryu¹

¹Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea
²Department of Radiology, Korea University College of Medicine, Seoul, Korea
³Department of Surgery, Korea University College of Medicine, Seoul, Korea

Correspondence: Hyung Joon Yim,
Email: gudwns21@medimail.co.kr

Abstract

Hepatic resection is a standard curative therapy for hepatocellular carcinoma (HCC) although only 10~30% of patients are indicated due to advanced stage or poor hepatic reserve. Five year survival rate after resection was reported as a mean of 55% (25~93%), but cases of early recurrence after hepatic resection had poor prognosis. As early recurrence after hepatic resection is the one of the most important factors that determines the prognosis, many investigators have been trying to determine the factors associated with early recurrence. We report a case of early multiple recurrence of HCC after curative hepatic resection probably due to microvascular invasion of tumor and too close resection margin. We would like to suggest that additional prophylactic measures need to be sought in this group of patients because these factors may influence on early recurrence.

Key Words: Hepatocellular carcinoma; Hepatic resection; Early recurrence

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