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Journal of the Korean Liver Cancer Study 2001;1(1):85-88.
Published online June 30, 2001.
A Case of Hepatocellular Carcinoma with Bile Duct Invasion
Seung Min Bang1, Hye Won Chung1, Jae Youn Cheong1, Chung Ryul Lee1, Kun Hoon Song1, Kwang Hyub Han1, Chae Yoon Cheon1, Young Myoung Moon1, Sung Il Park2, Do Yun Lee2, Jong Tae Lee2
1Department of Internal Medicine, Institute of Gastoroenterology, Yonsei University College of Medicine
2Department of Diagnostic Radiology, Department of Internal Medicine, Institute of Gastoroenterology, Yonsei University College of Medicine
Correspondence:  Kwang Hyub Han,
Email: gihankhys@yumc.ac.kr
Copyright ©2001 by The Korean Liver Cancer Association
A 52 year-old female patient with liver cirrhosis admitted due to icteric skin color for 3 weeks. Four months ago, she had been diagnosed as hepatocellular carcinoma(HCC), and treated with transarterial chemoembolization(TACE) at another hospital. Physical findings revealed that she had icteric sclera without ascites or palpable hepatosplenomegaly. Total bilirubin was 6.0mg/dL, ALT/AST was 117/111 IU/L. Computed tomography showed 3cm sized nodular mass involving left lateral segment of the liver and left intrahepatic bile duct. Endoscopic retrograde cholangiopancreatography(ERCP) revealed filling defect of left intrahepaitc duct and common hepatic duct, suggesting left intrahepatic duct and common hepatic duct invasion of HCC. After endoscopic retrograde biliary drainage(ERBD) with stent insertion, total bilirubin was decreased and clinical symptoms were improved. She was treated with TACE using adriamycin after ERBD. Thereafter, she was prescribed oral 5-fluorouracil and treated with external radiotherapy(4,500cGy). Five months later after the treatment, CT scan showed decrease in tumor size, and jaundice was improved as well.
Key Words: Bile duct invasion; Hepatocellular carcinoma; Chemoembolization


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