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Journal of the Korean Liver Cancer Study 2008;8(1):47-50.
Published online June 30, 2008.
A Case of Hepatocellular Carcinoma With Bile Duct Thrombi Presenting Obstructive Jaundice
Su Rin Shin1, Geum-Youn Gwak1, Cheol Keun Park2, Won Jae Lee3, Moon Seok Choi1, Joon Hyeok Lee1, Kwang Cheol Koh1, Seung Won Paik1, Byung Chul Yoo1
1Departments of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
2Departments of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
3Departments of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
Correspondence:  Geum-Youn Gwak,
Email: gy.gwak@samsung.com
Copyright ©2008 by The Korean Liver Cancer Association
Abstract
Although invasion into blood vessels, particularly the portal vein, is a common feature of hepatocellular carcinoma (HCC), intrabile duct invasion has been considered rare. HCC with bile duct thrombi is occasionally misdiagnosed as biliary carcinoma or stone, and tends to have a worse clinical course than HCC without bile duct thrombi, probably attributable to the low resectability rate secondary to poor functional reserve caused by obstructive jaundice, and combined major vascular invasion. However, a few data demonstrated that obstructive jaundice aroused an early detection of HCC, leading to a better survival. Herein, we describe a case of HCC with bile duct thrombi, which was diagnosed at an early stage with obstructive jaundice and had a favorable course after surgical resection.
Key Words: Hepatocellular carcinoma; Bile duct thrombi; Obstructive jaundice; Resection
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