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Journal of the Korean Liver Cancer Study 2007;7(1):94-97.
Published online June 30, 2007.
A Case of Advanced Hepatocellular Carcinoma with Portal Vein Thrombosis Treated by Intra-arterial Chemotherapy and Radiotherapy
Sang Gyune Kim, Young Seok Kim, Jae Young Jang, Su Jin Hong, Bong Min Ko, Chang Beom Ryu, Jong Ho Moon, Moon Sung Lee, Chan Sup Shim, Boo Sung Kim
Institute for Digestive Research, Department of Internal Medicine, SoonChunHyang University College of Medicine, Bucheon and Seoul, Korea
Correspondence:  Young Seok Kim,
Email: liverkys@schbc.ac.kr
Copyright ©2007 by The Korean Liver Cancer Association
Advanced hepatocelluar carcinoma (HCC) with portal vein thrombosis has a poor prognosis due to inadequate tumor response. 1 year survival rate and median surviral of stage IVa is less than 20%, 3 months respectively. Transarterial chemoembolization (TACE) was known to prolong the overall survival rate in patients with moderately advanced HCC. But, only small number of patients with stage IVa can receive the TACE. Other treatment modalities to manage for advanced HCC are systemic chemotherapy, hepatic arterial infusion chemotherapy or radiotherapy. Especially concurrent chemo-radiotherapy would be a better treatment option. We report a case of good response after repeated hepatic arterial infusion chemotherapy and radiotherapy for patient in advanced HCC with portal vein thrombosis.
Key Words: Hepatocellular carcinoma; Infusion chemotherapy; Radiotherapy


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