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Journal of the Korean Liver Cancer Study 2007;7(1):82-86.
Published online June 30, 2007.
A Case of Cyberknife Treatment for Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis
Chan Ran You1, Si Hyun Bae1, Hyun Young Woo1, Soung Won Jeong1, Jong Young Choi1, Seung Kew Yoon1, Hong Seok Jang2, Dong Hoon Lee3, Byung Gil Choi3
1Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea
2Department of Radiation Oncology, College of Medicine, The Catholic University of Korea, Seoul, Korea
3Department of Radiology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Correspondence:  Si Hyun Bae,
Email: baesh@catholic.ac.kr
Copyright ©2007 by The Korean Liver Cancer Association
A 64 year-old-male patient was transferred to our hospital for infiltrative hepatocellular carcinoma (HCC) without treatment response because of treatment failure and disease progression. He had been diagnosed infiltrating HCC 9 months ago and then treated with three times of transarterial chemolipiodolization (TACL) in other hospital. But, HCC was progressed. Abdominal CT showed infiltrating HCC in S7 and a small daughter nodule in S8 with right and main portal vein tumor thrombosis (PVTT). We performed stereotatic radiosurgery (Cyberknife) for the treatment of PVTT and four times of TACL for the treatment of intrahepatic HCC every 4weeks. The total radiation doses using with Cyberknife were 36Gy with a prescription isodose 80% in 3 fractions over the three consecutive days. After treatment, infiltrating HCC was decreased in size and PVTT was markedly regressed. Response rate of serum AFP was 57.2%. In conclusion, we report the case of good treatment response in the patient with HCC with PVTT after combination treatment of Cyberknife and TACL.
Key Words: Hepatocellular carcinoma; Portal vein tumor thrombosis; Cyberknife


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