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Journal of the Korean Liver Cancer Study 2007;7(1):77-81.
Published online June 30, 2007.
A Case of Advanced Hepatocellular Carcinoma with Inferior Vena Caval Invasion, Resected with a Curative Aim after Concurrent Chemo-Radiation Therapy
Seung Up Kim1, Kwang Hyub Han1,2,3, Jin Sil Sung3,4, Do Young Kim1,2,3, Sang Hoon Ahn1,2,3, Gyeong Sig Kim3,5, Young Nyun Park3,6, Chae Yoon Chon1,2,3
1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea
2Yonsei Liver Cancer Study Group, Yonsei University College of Medicine, Seoul, Korea
3Liver Cirrhosis Clinical Research Center, Yonsei University College of Medicine, Seoul, Korea
4Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, Korea
5Department of Surgery, Yonsei University College of Medicine, Seoul, Korea
6Department of Pathology, Yonsei University College of Medicine, Seoul, Korea
Correspondence:  Do Young Kim,
Email: dyk1025@yumc.yonsei.ac.kr
Copyright ©2007 by The Korean Liver Cancer Association
Abstract
Hepatocellular carcinoma (HCC) with tumor thrombus in inferior vena cava (IVC) is difficult to treat. Therefore, there are no specific treatment modalities for such case. Here, we present a patient diagnosed as hepatocellular carcinoma with tumor thrombus in inferior vena cava (stage IVa). The patient was treated with concurrent chemo-radiation therapy (CCRT) for 5 weeks. After that, tumor size was markedly decreased, and 9th courses of additional intra-arterial chemotherapy were performed. Follow-up positron emission tomography- computed tomography (PET-CT) showed shrinked hepatocellular carcinoma and right lobe, disappearance of IVC tumor thrombus, decreased size of right hepatic vein thrombus and a faint uptake at gallbladder. Residual malignancy could not be excluded. So, right hepatic lobectomy with a curative aim was performed and its result was successful.
Key Words: Hepatocellular carcinoma; CCRT; Hepatic lobectomy
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