J Liver Cancer Search


Journal of the Korean Liver Cancer Study Group 2007;7(1):16-21.
Published online June 30, 2007.
Radiology of the Combined HCC and CC
Jin-Young Choi
Department of Radiology, Seoul National University Hospital, Department of Diagnostic Radiology, Yonsei University College of Medicine, Seoul, Korea
Correspondence:  Jin-Young Choi,
Email: gafield2@yumc.yonsei.ac.kr
Combined hepatocellular-cholangiocarcinoma (HCC-CC) is a rare tumor showing histological evidence of both hepatocellular and biliary epithelial differentiation. Because of its rarity, there have been few reports about the imaging findings of this tumor. The CT findings of the combined HCC-CC include well-defined tumor with signs of malignancy such as hepatic hypervascularity, biliary obstruction, satellite nodules, and lymphadenopathy. Some portions may show hypoattenuation on arterial phase, whereas other portions show delayed persistent enhancement. The signal intensity of this tumor on magnetic resonance (MR) imaging is not specific. However, when the tumor resembles cholangiocarcinoma on gross pathologic exam, it shows peripheral rim-like enhancement, infiltrative margin, and portal vein invasion in patients with liver cirrhosis. On the other hand, when the tumor has gross appearance of HCC, imaging findings are not helpful for diagnosis. Cross-sectional imagings are helpful for predicting the predominant component of the combined HCC-CC and determining the treatment strategy.
Key Words: Combined hepatocellular-cholangiocarcinoma, Computed tomography, Magnetic resonance imaging, Liver; Computed tomography; Magnetic resonance imaging, Liver
Share :
Facebook Twitter Linked In Google+ Line it
METRICS Graph View
  • 402 View
  • 8 Download
Related articles in J Liver Cancer

Editorial Office
620 Yeoksam Heights Bldg.(FASTFIVE),151 Teheran-ro, Gangnam-gu, Seoul 06132, Korea
Tel: +82-2-313-1900    E-mail: liver@klcsg.or.kr                

Copyright © 2022 by The Korean Liver Cancer Association.

Developed in M2PI

Close layer
prev next