With advances in the diagnosis and local treatement of HCC, which have resulted in a prolongation of survival,
extrahepatic metastasis of HCC influence the survival of HCC patients. In particular, the frequency of death due
to respiratory failure resulting from pulmonary metastases, pain and fractures resulting from bone metastases has
been increased gradually. The efficacy of systemic treatment for the extrahepatic metastases is discouraging
because of a lack of effective chemotherapeutic agents, reduced hepatic reserve and adverse effects. We report one
case
of the prolonged survival in a patient with hepatocellular carcinoma after treatment of bone and lung
metastases.