J Liver Cancer Search


Journal of the Korean Liver Cancer Study Group 2006;6(1):52-55.
Published online June 30, 2006.
A Case of Advanced Hepatocellular Carcinoma Treated with Hepatic Arterial Infusion Chemotherapy
So Yeon Lee1, Si Hyun Bae1, Min Su Kim1, Jong Young Choi1, Seung Kew Yoon1, Dong Hoon Lee2, Ho Jong Choen2
1Departments of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea
2Departments of Radiation, College of Medicine, The Catholic University of Korea, Seoul, Korea
Correspondence:  Si Hyun Bae,
Email: baesh@catholic.ac.kr
A 57 year-old-male patient was admitted to our hospital for evaluation of hepatic mass which was detected on ultrasonography. He had history of chronic hepatitis B and alcoholism. Laboratory findings showed that HBsAg was positive, and HBeAg was negative. AFP was 5.39 ng/mL. Abdominal CT showed large ill-defined low density lesion in 4, 7 and 8 segment of the liver with tumor thrombosis at umbilical portion of left portal vein, which was compatible with advanced hepatocellular carcinoma (stage IVb). Celiac and hepatic arteriogram revealed huge hypervascular mass at both lobe of the liver. Chemoport catheter was inserted to the right hepatic artery and intra-arterial chemotherapy (epirubicin 50 mg every 4 weeks, cisplatin 25 mg and 5-FU 200 mg weekly) was started with continuous infusion device. After 3 cycles of repeated intra-arterial chemotherapy, tumor mass in both hepatic lobe were decreased in size and extent. He is planned to be treated with additional intra-arterial chemotherapy.
Key Words: Hepatocellular carcinoma; Treatment; Hepatic-arterial infusion chemotherapy

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