Abstract

A 57 year-old-male patient was admitted to our hospital for evaluation of hepatic mass which was detected on ultrasonography. He had history of chronic hepatitis B and alcoholism. Laboratory findings showed that HBsAg was positive, and HBeAg was negative. AFP was 5.39 ng/mL. Abdominal CT showed large ill-defined low density lesion in 4, 7 and 8 segment of the liver with tumor thrombosis at umbilical portion of left portal vein, which was compatible with advanced hepatocellular carcinoma (stage IVb). Celiac and hepatic arteriogram revealed huge hypervascular mass at both lobe of the liver. Chemoport catheter was inserted to the right hepatic artery and intra-arterial chemotherapy (epirubicin 50 mg every 4 weeks, cisplatin 25 mg and 5-FU 200 mg weekly) was started with continuous infusion device. After 3 cycles of repeated intra-arterial chemotherapy, tumor mass in both hepatic lobe were decreased in size and extent. He is planned to be treated with additional intra-arterial chemotherapy.

• Keywords: Hepatocellular carcinoma;Treatment;Hepatic-arterial infusion chemotherapy