Abstract

A 46 year-old male patient was admitted to our hospital for evaluation of hepatic mass which was detected on ultrasonography. He had a history of chronic hepatitis B carrier. Laboratory findings showed that HBsAg was positive, and HBeAg was negative. AFP was 2,081.1 ng/mL. Abdomen CT showed a large well-defined low density lesion involving entire right hepatic lobe which was compatable with advanced hepatocellular carcinoma (stage III). Celiac and hepatic arteriogram reveled huge hypervascular mass at both lobe of the liver. Transcatheter arterial chemoembolization (TACE), systemic chemotherapy, percutaneous ethanol injection therapy (PEIT), and radiotherapy were combined as the treatment of huge hepatoma. After combined therapy, tumor decreased in size. As a result, curative right lobectomy could be performed. Six months after surgery, chest CT showed two small metastatic nodules in both lung, so wedge resection was performed. We followed the patient for 5 years after operation and there was no evidence of regional tumor recurrence or distant metastasis.

• Keywords: Hepatocellular carcinoma;Treatment;Transcatheter arterial chemoembolization;Surgical treatment