Abstract

Advanced hepatocellular carcinoma (HCC) suggests a significantly high risk of recurrence, and the role of hepatic resection for advanced HCC is unclear. We will describe two cases of advanced HCC treated by hepatic resection. The two patients had liver tumors greater than 10 cm in diameter, with good liver function, and without tumor invasion to the main portal vein. The hepatic resection types were 5, 6 segmentectomy and hemihepatectomy. The lengths of surgical margins were 4.5 cm and 3.0 cm, each. In one patient, tumor invasion to resected diaphragm was detected in the 1st operation specimen. This patient received the second and third operation due to local recurrence. All these patients survived over 3 years without tumor recurrence. The hepatic resection for large HCC and repeated resection for local recurrence in selected cases can put in the way of long-term survival and cure.

• Keywords: Hepatocellular carcinoma;Surgery;Long-term survival