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HOME > J Liver Cancer > Volume 26(2); 2026 > Article
Special Contribution Stereotactic body radiation therapy for hepatocellular carcinoma: 2026 expert consensus-based practical recommendation of the Korean Liver Cancer Association
Jinhong Jung1*orcid , Han Ah Lee2*orcid , Do Young Kim3orcid , Hyun-Cheol Kang4orcid , Sun Hyun Bae5orcid , Ji Hye Min6orcid , Gyu Sang Yoo7orcid , Jeong Il Yu8orcid , Seo Hee Choi9orcid , Hae Lim Lee10orcid , Subin Heo11orcid , Chai Hong Rim12orcid , Sang Min Yoon1orcid , June Sung Lee13orcid , Research Committee of the Korean Liver Cancer Association
Journal of Liver Cancer 2026;26(2):182-204
DOI: https://doi.org/10.17998/jlc.2026.08.22
Published online: September 2, 2026
1Department of Radiation Oncology, Asan Liver Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
2Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea
3Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea
4Department of Radiation Oncology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea
5Department of Radiation Oncology, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea
6Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
7Department of Radiation Oncology, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Korea
8Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
9Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Yonsei University Health System, Seoul, Korea
10Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea
11Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
12Department of Radiation Oncology, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Korea
13Division of Gastroenterology, Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea
Corresponding author:  Sang Min Yoon,
Email: drsmyoon@amc.seoul.kr
June Sung Lee,
Email: jsleemd@paik.ac.kr
Received: 9 July 2026   • Revised: 5 August 2026   • Accepted: 22 August 2026
Jinhong Jung and Han Ah Lee contributed equally to this study as co-first authors.
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Stereotactic body radiation therapy (SBRT) is a noninvasive, high-precision radiation technique that delivers a high dose to the tumor in a limited number of fractions, typically five or fewer, and is increasingly used as a curative-intent option for hepatocellular carcinoma (HCC), particularly when surgical resection, liver transplantation, or local ablative therapies are not feasible. Although domestic and international guidelines have incorporated SBRT into the treatment algorithm for HCC, the lack of comprehensive evidence and expert opinion regarding patient selection, pretreatment evaluation, treatment planning and delivery, complication management, and post-treatment follow-up has resulted in substantial variation in clinical practice. Accordingly, expert consensus-based practical recommendations for SBRT were developed by a group of radiation oncologists, hepatologists, and radiologists from the Research Committee of the Korean Liver Cancer Association, based on expert surveys, a comprehensive review of evidence-based literature, and a modified Delphi process. Encompassing the entire clinical workflow of liver SBRT, these recommendations are intended to provide practical guidance for the safe and effective implementation of SBRT in patients with HCC.


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