Journal of Liver Cancer

Case Reports

A Case of Hepatocellular Carcinoma in Young Age Younger than 20 Years Old: Joo Won Chung, Seung Up Kim, Jun Yong Park, Sang Hoon Ahn, Kwang-Hyub Han, Chae Yoon Chon, Geung-kyu Ko, Jin Sil Seong, Jong Hee Chang, Do Young Kim; Journal of the Korean Liver Cancer Study Group. 2009;9(1):71-75. Published online June 30, 2009

Abstract PDF: Hepatocellular carcinoma (HCC) is very rare in young age. Most young patients tend to receive the evaluation only when they experience intractable or persistent symptoms. Therefore, HCC in young patients is often diagnosed at advanced stage and thus, young HCC patients have a worse prognosis than older HCC. However, because young HCC patients show well-preserved liver function than older HCC, they are tolerable to more aggressive treatments. We report a case of advanced HCC in 13-year and 8-month old male who has been a B-viral carrier. Despite the tumor size decreased after concurrent chemoradiation therapy, multiple lung and brain metastases developed. He underwent radiofrequency ablations on lung metastases and gamma-knife surgery on brain metastasis, and he has received systemic and intra-arterial chemotherapy. The screening and early diagnosis of HCC in young age is needed especially for B-viral carrier with a family history of HCC.

A Case of Advanced Hepatocellular Carcinoma in Twenties Treated by Multimodality Therapy: Jang Eun Lee, Na Ri Yoon, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon, Dong Goo Kim, Ho Jong Chun, Byung Gil Choi, Hae Giu Lee, Hong Seok Jang, Chan Kwon Jung, Eun Sun Jang; Journal of the Korean Liver Cancer Study Group. 2009;9(1):82-85. Published online June 30, 2009

Abstract PDF: The prognosis of young patients with hepatocellular carcinoma is remains controversial. Here we report a case of advanced hepatocellular carcinoma in twenty, successfully treated with transarterial chemolipidolization (TACL), systemic chemotherapy, radiation therapy and surgical resection. Previously healthy 28 years old woman was admitted for treatment of hepatocellular carcinoma. Abdominal CT showed a diffuse infiltrative HCC involving both lobes with intrahepatic bile duct invasion and pericardial lymphadenopathy. She was treated TAC with systemic chemotherapy and external beam radiotherapy. 6 months after these treatments, main tumor and the pericardial lymph node were decreased in size. And then extended left lobectomy and systemic chemotherapy were done. The pericardial lymph node was markedly decreased. The patient has been followed for 10 months without evidence of regional tumor recurrence.

A Case of Hepatocellular Carcinoma in a Young Patient with Suspected Autoimmune Hepatitis: Yu Jin Kim, Sang Hoon Park, Kyung Rim Huh, Kyung Hoon Lee, Tae Ho Hahn, Dong Joon Kim, Myung Seok Lee, Choong Kee Park, Min Jeong Kim, Soo Ki Min; Journal of the Korean Liver Cancer Study Group. 2009;9(1):94-97. Published online June 30, 2009

Abstract PDF: Whether the prognosis of hepatocellular carcinoma in young patients is different from elderly patients is still controversial. Previous reports revealed that most of the young hepatocellular carcinoma patients have hepatitis B viral infection, larger tumor and more advanced stage than elderly patients, and these features not just young age are related with poor survival. We experienced a case of stage IVA hepatocellular carcinoma suspected to be related with autoimmune hepatitis in a 28-year-old man. Even though 3 times of transarterial chemoembolization and best supportive care were given, he died 7 months after diagnosis.

Search