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JLC : Journal of Liver Cancer

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6 "Tumor thrombus"
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Case Reports
Living Donor Liver Transplantation for Hepatocellular Carcinoma with Portal Vein Tumor Thrombus
YoungRok Choi, Kwang-Woong Lee, Hae Won Lee, Nam-Joon Yi, Kyung-Suk Suh
Journal of the Korean Liver Cancer Study Group. 2013;13(1):62-64.   Published online February 28, 2013
DOI: https://doi.org/10.17998/jlc.13.1.62
  • 1,289 Views
  • 8 Downloads
AbstractAbstract PDF
Malignant portal vein thrombosis is a contraindication to liver transplantation for hepatocellular carcinoma because of the high risk of its recurrence and the poor patient survival. With a newly developed immunosuppressant and a chemotherapeutic agent, however, living donor liver transplantation can be considered for a patient of hepatocellular carcinoma, showing a slow growth rate and good response for transarterial chemoembolization. We report a HBV related liver cirrhosis patient with HCC and portal vein tumor thrombus who underwent living donor liver transplantation and survived without recurrence of hepatocellular carcinoma for 18 months in our center.
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A Case of Hepatocellular Carcinoma with Tumor Thrombus in Inferior Vena Cava and Right Atrium
Hyun Jung Lee, Hyung Joon Yim, Hwan Hoon Chung, Seung Hwa Lee, Hae Rim Kim, Jong Jin Hyun, Sung Woo Jung, Ja Seol Koo, Sang Woo Lee, Jai Hyun Choi
Journal of the Korean Liver Cancer Study Group. 2012;12(2):141-145.   Published online September 30, 2012
  • 679 Views
  • 2 Downloads
AbstractAbstract PDF
In patients with advanced hepatocellular carcinoma (HCC), tumor thrombus in inferior vena cava (IVC) and right atrium (RA) are not uncommon findings and are usually associated with extremely poor outcome. Although aggressive surgical interventions such as extracorporeal circulation and tumor excision have been performed, the reported results were still unsatisfactory. Herein, we report the favorable result of combined treatment with radiation therapy and transarterial chemoembolization in a patient with advanced HCC with extensive tumor thrombus through the IVC into the RA. In conclusion, noninvasive combined modalities, such as transarterial chemoembolization and radiation therapy may sometimes provide effective palliation for patients with far advanced HCC with IVC/RA tumor thrombus and who are not candidates for alternative treatment options.
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A Case of Hepatocellular Carcinoma with Portal Vein Tumor Thrombi which was Performed Hepatectomy after Down-staging by Proton Therapy
Hee-Jung Wang, Bong-Wan Kim, Wei-Kwang Xu
Journal of the Korean Liver Cancer Study Group. 2011;11(1):56-59.   Published online February 28, 2011
  • 635 Views
  • 1 Download
AbstractAbstract PDF
A case of hepatocellular carcinoma (HCC) with portal vein tumor thrombi (PVTT) which was performed hepatectomy after down-staging by proton therapy is reviewed. Generally, the recommended therapeutic strategy for this kind of HCC is radiation therapy, systemic or infusion anticancer chemotherapy. However, the response of HCC and its PVTT of this 56 year-old male patient was relatively good after 22 times of proton therapy, and we performed right hemihepatectomy on the concept of clinical trial under the informed consent of patient and his families. He is still alive without recurrence 15 months after hepatectomy. We suggest that hemihepatectomy with removal of PVTT could be an alternative strategy in the PVTT accompanied HCC cases who show good responses after the above generally recommended therapies.
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A Case of Hepatocelluar Carcinoma with Portal Vein Tumor Thrombus arterial
Jong Kyu Park, Young Seok Kim, Sang Gyune Kim, Seung Won Jeong, Jae Young Jang, Hyun Jong Choi, Jong Ho Moon, Hong Soo Kim, Moon Sung Lee, Chan Sup Shim, Boo Sung Kim
Journal of the Korean Liver Cancer Study Group. 2009;9(1):49-52.   Published online June 30, 2009
  • 523 Views
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AbstractAbstract PDF
Recent progress in imaging techniques has permitted the diagnosis of hepatocelluar carcinoma (HCC) at an early stage. However, portal vein invasion is still found in 12.5~39.7%. HCC with tumor thrombosis of the portal vein has a poor prognosis. Previous studies showed that the median survival time of patients with HCC with involving portal vein was 2.7~4 months if effective treatment was not administered. Thus, for such HCC with portal vain invasion, an effective therapy that will maintain quality of life is required. We report a case of HCC with portal vein tumor thrombus treated by intra-arterial chemotherapy.
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A Case of Successful Hepatic Resection for Hepatocellular Carcinoma with Tumor Thrombus Extending into the Right Atrium
Yong Beom Cho, Kuhn Uk Lee, Hyo-Suk Lee, Hyuk Ahn, Hae Won Lee, Eung-Ho Cho, Sung-Hoon Yang, Jai Young Cho, Nam-Joon Yi, Kyung-Suk Suh
Journal of the Korean Liver Cancer Study Group. 2006;6(1):25-27.   Published online June 30, 2006
  • 602 Views
  • 4 Downloads
AbstractAbstract PDF
Hepatocellular carcinoma (HCC) with extension of its tumor thrombus into the inferior vena cava (IVC) and right atrium has been regarded as beyond the realm of surgical resection. It could cause sudden death due to pulmonary embolism or heart failure by the detached fragments of tumor thrombus. In recent years, successful surgery has been reported for hepatic malignancies with its tumor thrombus to the IVC and right atrium by some centers of Taiwan and Japan. We also did a successful en bloc resection of the liver tumor and its tumor thrombus in the IVC and right atrium using cardiopulmonary bypass and report herein.
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A Case of Successful Hepatic Resection after Transarterial Chemoembolization and Perfusion Chemotherapy for Huge Hepatocellular Carcinoma with Tumor Thrombus Extending into the Inferior Vena Cava
Yong Beom Cho, Kuhn Uk Lee, Hyo-Suk Lee, Jae Hyung Park, Hae Won Lee, Eung-Ho Cho, Sung-Hoon Yang, Jai Young Cho, Nam-Joon Yi, Kyung-Suk Suh
Journal of the Korean Liver Cancer Study Group. 2006;6(1):28-31.   Published online June 30, 2006
  • 543 Views
  • 1 Download
AbstractAbstract PDF
The use of transarterial chemoembolization (TACE) in the treatment of hepatocellular carcinoma (HCC) has become increasingly popular in the last 20 years. By TACE overall survival might be prolonged in patients with moderately advanced HCC, and some surgically untreatable tumors have been rendered resectable subsequently and some patients achieved cures. However, it would be recommended to proceed with liver resection when we were unable to ascertain clinically the complete success of post-TACE tumor destruction, even when the size of the huge tumor was reduced obviously and the alpha-fetoprotein returned to normal after TACE treatments. Sequential surgical resection has been advocated for a curative outcome even after effective TACE treatments. We report a case of successful hepatic resection with right hepatic vein and its adjacent IVC after TACE and perfusion chemotherapy for huge HCC with tumor thrombus extending into IVC.
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JLC : Journal of Liver Cancer