Journal of Liver Cancer

1 "Three-dimensional conformal radiation therapy"

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Case Report

Effect of combination therapy with TACE and 3D-CRT for two patients with PVT and/or IVC tumor thrombus: Hyun Deok Shin, Young-Suk Lim, Soon Joo Kim, Sang Hyun Park, Gang Mo Kim, Han Chu Lee, Young Hwa Jung, Young Sang Lee, Dong Jin Suh; Journal of the Korean Liver Cancer Study Group. 2007;7(1):87-93. Published online June 30, 2007

Abstract PDF: Advanced hepatocellular carcinoma has a poor prognosis, especially in the cases with portal vein or IVC tumor thrombi. In such cases, surgical resection could not be a curative treatment option and transcatheter arterial chemoembolization (TACE) alone is usually ineffective. Recently, three-dimensional conformal radiation therapy (3D-CRT) has been developed to better conform the radiation dose to the tumor volume in order to reach the goal of eradicating local disease without injuring normal tissue. Combination therapy with TACE and 3D-CRT could be considered as a treatment option for advanced HCC with PV or IVC tumor thrombi. We report here two cases with advanced HCC showing response to combination therapy with repeated TACE and 3D-CRT.

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