Proton beam therapy (PBT) is one of the advances in radiotherapy techniques, which enables dose escalation with lower probability of radiation-induced liver or gastrointestinal injuries. However, the chest wall proximal to the tumor can be affected by high dose irradiation. Here, we report on a 58-year-old male patient who presented with huge hepatocellular carcinoma, received treatment with transarterial chemoembolization and PBT, and developed severe chest wall pain due to radiation-induced myositis. The patient’s symptoms were controlled by oral steroids.
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Pectoralis Major Radiation Myonecrosis After Lung Stereotactic Body Radiation Therapy Jason Gurewitz, Anand Mahadevan, Benjamin T. Cooper Practical Radiation Oncology.2024; 14(3): 189. CrossRef
Current role of proton beam therapy in patients with hepatocellular carcinoma Gyu Sang Yoo, Jeong Il Yu, Hee Chul Park International Journal of Gastrointestinal Intervention.2021; 10(4): 175. CrossRef
Although first-line treatment option for single, small sized hepatocellular carcinoma in patients with preserved liver function and good performance status is resection or ablation, sometimes these modalities cannot be applied for variable reasons. For them, alternative options such as transarterial chemoeombolization, ethanol injection, and external radiation therapy can be considered, with variable success rates. Herein, we describe 45 year-old male who presented with a single small tumor located at caudate lobe. After multi-disciplinary discussion, the patient was treated with proton beam therapy, which resulted in favorable treatment outcome.
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Carbon ion radiotherapy for patients with hepatocellular carcinoma in the caudate lobe Shohei Okazaki, Kei Shibuya, Shintaro Shiba, Masahiko Okamoto, Yuhei Miyasaka, Naoto Osu, Motohiro Kawashima, Satoru Kakizaki, Kenichiro Araki, Ken Shirabe, Tatsuya Ohno Hepatology Research.2021; 51(3): 303. CrossRef