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JLC : Journal of Liver Cancer

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5 "Portal vein thrombosis"
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Case Reports
A Case of Hepatocellular Carcinoma with Portal Vein Thrombi Successfully Treated with TACE Following Radiation Therapy
Won Sub Choi, Sang Hoon Park, Kyung Rim Huh, Kyung Hun Lee, Tae Ho Hahn, Choong Kee Park, Min Jeong Kim, Eui-Yong Jeon, Su Ssan Kim
Journal of the Korean Liver Cancer Study Group. 2008;8(1):106-110.   Published online June 30, 2008
  • 648 Views
  • 3 Downloads
AbstractAbstract PDF
Transarterial chemoembolization (TACE) is one of treatment modalities which can give survival benefit to patients with hepatocellular carcinoma (HCC) to which curative therapies can be applied. But, TACE can encounter the risk of liver failure in case of HCC with main portal vein tumor thrombi. Advances in techniques to account for respiration motion and understanding of partial liver tolerance to radiation therapy have permitted us to deliver high dose radiation therapy without toxicity in treatment of HCC. We report a case of HCC with massive portal vein thrombosis which responded to TACE following radiation therapy.
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A Case of Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis Achieving Complete Response with New Therapeutic Modalities
Hyun Young Woo, Jin Dong Kim, Jung Hyun Kwon, Chan Ran You, Jeong Won Jang, Si Hyun Bae, Jong Young Choi, Se Hyun Cho, Seung Kew Yoon, Dong Hoon Lee, Ho Jong Chun, Byung Gil Choi, Chul Seung Kay
Journal of the Korean Liver Cancer Study Group. 2008;8(1):124-127.   Published online June 30, 2008
  • 888 Views
  • 1 Download
AbstractAbstract PDF
A 45-year-old man was admitted for the treatment of hepatocellular carcinoma (HCC). He was diagnosed hepatitis B carrier 16 years ago and has not done a routine check. Abdominal CT showed a diffuse infiltrative HCC involving right hepatic lobe with portal vein tumor thrombosis (PVTT) involving right portal vein and proximal portion of left portal vein umbilical portion. With concurrent transcatheter arterial chemotherapy (TAC), helical tomotherapy for portal vein thrombosis was done. With these treatments, main tumor and PVTT was decreased in size markedly and no stain in hepatic angiogram. Due to repeated TAC, hepatic arterial stenosis occurred and TAC was stopped. 3 months after, recurrent tumor was detected in MRI. Radiofrequency ablation followed by High Intensity Focused Ultrasound (HIFU) was done for this recurrent mass. No viable mass was shown in the follow up MRI done 6 months after HIFU.
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A long-term survival case of advanced hepatocellular carcinoma with portal vein thrombosis successfully treated with multimodal treatments
Ju Hyun Choi, Han Eul Song, Chang Il Kwon, Kwang Hyun Ko, Sung Pyo Hong, Seong Gyu Hwang, Pil Won Park, Kyu Sung Rim, Man Deuk Kim, Sung Won Kwon
Journal of the Korean Liver Cancer Study Group. 2007;7(1):66-70.   Published online June 30, 2007
  • 679 Views
  • 1 Download
AbstractAbstract PDF
We reported a 52-year-old women with hepatocellular carcinoma (HCC) of 10 cm in diameter involving entire right lobe with advanced tumor thrombosis in the both branches and main trunk of portal vein. She was treated with multimodal treatments resulting in a long-term survival of more than 5 years. At first, she was treated with hepatic arterial chemotherapy (HAC) using cisplatin and 5-FU for 5 cycles and radiation therapy in September 2002. The tumor size decreased and the main and left portal vein thrombosis was disappeared. Although, she had been treated with the 3th radiofrequency ablation (RFA) and the 3th transarterial chemoembolization (TACE) three times for the treatment of main tumor, follow-up CT scan still showed marginal viable tumor at the segment 5. Therefore, she was underwent right lobectomy of the liver and splenectomy. Further TACE was performed once for the small remnant tumor around inferior vena cava at the postoperative 4 months. Finally, she has been survived for over 5 years from the initial treatment and 23 months after operation without evidence of recurrence. We suggest that the long-term survival was achieved in this patient through appropriate treatment selections at the right time, such as HAC, RFA, TACE, hepatic resection and external radiotherapy based on changes in diagnostic imaging and tumor markers.
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Two Cases of Good Response after Intra-arterial Chemotherpy in Patients with Advanced Hepatocellular Carcinoma
Youn Ho Kim, Yong Sik Kim, Youn Tae Jeen, Hoon Jae Jun, Soon Ho Um, Chang Duk Kim, Ho Sang Ryu
Journal of the Korean Liver Cancer Study Group. 2006;6(1):47-51.   Published online June 30, 2006
  • 715 Views
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AbstractAbstract PDF
Advanced hepatocellular carcinoma has a poor prognosis, especially in the case of advanced hepatocelluar carcinoma with portal vein thrombosis. In such cases, variable therapeutic modalities have been tried to improve the prognosis. Intra-arterial chemotherapy is one of these modalities, but the effect of this therapeutic modality is unclear. We report two cases of good response after intra-arterial chemotherpy in patients with advanced hepatocellular carcinoma.
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Report of Two Patients Treated with 3-Dimensional Conformal Radiotherapy for Hepatocellular Carcinoma
Kyung Woo Park, Joong-Won Park, Sang-Hyung Cho, Young Il Kim, Seong Hoon Kim, Hong Suk Park, Woo Jin Lee, Sang Jae Park, Dae Young Kim, Eun Kyoung Hong, Chang-Min Kim
Journal of the Korean Liver Cancer Study Group. 2005;5(1):37-41.   Published online June 30, 2005
  • 728 Views
  • 2 Downloads
AbstractAbstract PDF
Recently, radiotherapy is considered as one of the palliative treatment modalities for patients with hepatocellular carcinoma. In the adevent of 3-dimensional conformal radiotherapy, liver can be treated with high dose radiotherapy without increment of complication. We report two cases of hepatocellular carcinoma with main portal vein thrombosis, who were treated with 3D-CRT and showed promising outcome.
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