In cases of lymph node metastasis in hepatocellular carcinoma (HCC), there is still no known effective
treatment. Extrahepatic lymph node metastasis of HCC have been treated by radiotherapy alone to achieve the
salvage of the disease or symptom palliation until a recent date. We would like to present a HCC case with lymph
node metastasis. He was treated with transarterial chemoemblization (TACE) and external beam radiotherapy
(RT) for the intra-hepatic masses and intraabdominal lymph nodes, respectively. 5-Months after the treatment,
multiple lipiodol uptaken masses and markedly decreased nodes were seen in CT scan. In spite of the partial
response of metastatic nodes with RT, the patient died of hepatic failure and recurrence of HCC. We can conclude
that RT is an effective treatment modality for metastatic lymph nodes of HCC and can be considered in patients
who have both controllable HCC and extrahepatic lymph node metastasis.
A 52-year-old man who underwent left hepatectomy with lymph node dissection due to hepatocellular carcinoma with lymph node metastasis. After 5 months of surgery, multiple recurrences were founded throughout the liver, lung, bones and intraperitoneal lymph nodes. The patient died of liver failure after rupture of recurrent hepatic tumor. From our experience, we reaffirmed that the prognosis of patients with nodal metastasis from hepatocellular carcinoma was generally poor, even after hepatic resection with lymph node dissection was performed.