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JLC : Journal of Liver Cancer

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Review Article
Liver Transplantation in Mixed Hepatocellular Carcinoma and Cholangiocarcinoma
Jong Man Kim
J Liver Cancer. 2019;19(2):85-90.   Published online September 30, 2019
DOI: https://doi.org/10.17998/jlc.19.2.85
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AbstractAbstract PDF
Mixed hepatocellular carcinoma and cholangiocarcinoma (HCC-CC) are rare tumors, and the risk factors associated with them are not well understood yet. Moreover, the diagnosis of mixed HCC-CC can be complicated due to the difficulty in distinguishing mixed HCC-CC from HCC and intrahepatic CCC on radiological images. Serum tumor markers are useful when the radiological images are inconclusive. It remains unclear whether the prognosis of mixed HCC-CC differs from that of HCC. However, several studies have reported that the tumor recurrence and patient survival rates of mixed HCC-CC were similar to those of HCC after liver transplantation (LT) and liver resection. In this paper, we report that LT in patients with mixed HCC-CC achieves outcomes which are similar to those seen in LT for HCC. Therefore, the diagnosis of mixed HCC-CC should not be considered as a contraindication for LT.

Citations

Citations to this article as recorded by  
  • Liver transplantation for combined hepatocellular carcinoma and cholangiocarcinoma: A multicenter study
    Jongman Kim, Dong-Jin Joo, Shin Hwang, Jeong-Moo Lee, Je-Ho Ryu, Yang-Won Nah, Dong-Sik Kim, Doo-Jin Kim, Young-Kyoung You, Hee-Chul Yu
    World Journal of Gastrointestinal Surgery.2023; 15(7): 1340.     CrossRef
  • The Role of Immunosuppression for Recurrent Cholangiocellular Carcinoma after Liver Transplantation
    Safak Gül-Klein, Paulina Schmitz, Wenzel Schöning, Robert Öllinger, Georg Lurje, Sven Jonas, Deniz Uluk, Uwe Pelzer, Frank Tacke, Moritz Schmelzle, Johann Pratschke, Ramin Raul Ossami Saidy, Dennis Eurich
    Cancers.2022; 14(12): 2890.     CrossRef
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