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Review Article
- Roles of Surgical Treatment for Patients with Advanced Hepatocellular Carcinoma
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Hyung Jun Kwon, Yoon Jin Hwang
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Journal of the Korean Liver Cancer Study Group. 2011;11(2):104-110. Published online September 30, 2011
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Abstract
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- Hepatic resection for Hepatocellular carcinoma (HCC) is potentally curative treatment for selected patients. However, the
roles of surgical treatment for advanced hepatocellular carcinoma are still uncertain. Although aggressive surgical approach is not
recommandable to all patients with advanced HCC, it is clear there is a group of patients that will benefit. In this review article,
the authors would like to examine the roles of surgical treatment for patients with advanced hepatocellular carcinoma (HCC) by
ascertaining the feasiability and results of surgical resection.
Case Reports
- A Case of Hepatocellular Carcinoma with Early Multiple Recurrences after Liver Resection
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Jae Hong Ahn, Hyung Joon Yim, Seung Young Kim, Jeong Han Kim, Yeon Seok Seo, Seung Hwa Lee, Hwan Hoon Chung, Tae Jin Song, Hong Sik Lee, Sang Woo Lee, Soon Ho Um, Jai Hyun Choi, Ho Sang Ryu
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Journal of the Korean Liver Cancer Study Group. 2009;9(1):29-32. Published online June 30, 2009
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Abstract
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- Hepatic resection is a standard curative therapy for hepatocellular carcinoma (HCC) although only 10~30% of patients are
indicated due to advanced stage or poor hepatic reserve. Five year survival rate after resection was reported as a mean of
55% (25~93%), but cases of early recurrence after hepatic resection had poor prognosis. As early recurrence after hepatic
resection is the one of the most important factors that determines the prognosis, many investigators have been trying to
determine the factors associated with early recurrence. We report a case of early multiple recurrence of HCC after curative
hepatic resection probably due to microvascular invasion of tumor and too close resection margin. We would like to suggest
that additional prophylactic measures need to be sought in this group of patients because these factors may influence on early
recurrence.
- A Case of Massive Hepatocellular Carcinoma Treated by Hepatic Resection, which did not Respond to Transarterial Chemoembolization
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Jeong Han Kim, Hyung Joon Yim, Seung Young Kim, Jae Hong Ahn, Ji Hoon Kim, Yeon Seok Seo, Seung Hwa Lee, Hwan Hoon Chung, Tae Jin Song, Hong Sik Lee, Sang Woo Lee, Jai Hyun Choi
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Journal of the Korean Liver Cancer Study Group. 2009;9(1):63-66. Published online June 30, 2009
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Abstract
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- Surgical resection is the treatment of choice for hepatocellular carcinoma (HCC) in non-cirrhotic patients. The optimal
indication for resection is a single tumor in a suitable location for resection. However, limit of the tumor size is not clear.
We report a case of successful hepatic resection in patients with massive HCC sized more than 15 cm that did not respond
to transarterial chemoembolization (TACE). A 49-year-old male patient had received TACE two times for massive HCC.
However, the tumor size increased. Right hemihepatectomy was performed despite the extensive tumor size and underlying
liver cirrhosis. Ascites and wound infection were developed after resection, but the patient’s general condition got recovered
soon. Until 6 months after surgery, recurrence has not been detected. However, distant metastasis was noted at 7th month.
Although recurrence with distant metastasis was noted, we think aggressive surgical approach prolonged this patient’s
survival.
Review Articles
- Hepatic Resection Following Adjuvant Treatments in Hepatocellular Carcinoma
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Sae-Byeol Choi, Kyung Sik Kim
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Journal of the Korean Liver Cancer Study Group. 2008;8(1):32-38. Published online June 30, 2008
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Abstract
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- The optimal treatment of hepatocellular carcinoma has become increasingly complex with myriad of available
treatment options. Although recently the liver transplantation has been accepted the best treatment for survival,
the shortage of donor limits the extension of this procedures. As the neoadjuvant chemotherapy is being
increasingly employed to downsize colorectal metastasis, the clinical trials have been extended to the
hepatocellular carcinoma. Therefore we reviewed the use of liver resection following tumor downstaging with
chemotherapeutic agents and Radiation therapy to treat unresectable HCC.
Key Words: Hepatic resection․Downstaging․Transarterial chemoembolization․Radiation
- Surgical Treatment in Advanced Hepatocellular Carcinoma
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Kyung Sik Kim
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Journal of the Korean Liver Cancer Study Group. 2006;6(1):1-6. Published online June 30, 2006
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Abstract
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- Hepatic resection has been accepted as one of the most effective treatments for hepatocelluar carcinoma. The
various advancements in both operative procedures and perioperative patient management have made the hepatic
resection safer and the indications for resection have been also expanded. Recently the International Cooperative
Study Group for hepatocellular carcinoma proposed a new staging based on data form multiple centers across the
world. According to this new staging, the paradigm of managing advanced hepatocellular carcinoma is being
changed. Therefore the experiences on the surgical approach to various situations such as larger HCC above 10
cm in diameter, vascular invasion and lymph node involvement were reviewed.
- Postoperative Early Multinodular Intrahepatic Recurrence of Hepatocellular Carcinoma
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Jeong Ho Park, Kwang Cheol Koh
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Journal of the Korean Liver Cancer Study Group. 2004;4(1):12-15. Published online June 30, 2004
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