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JLC : Journal of Liver Cancer

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6 "Hepatic resection"
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Review Article
Roles of Surgical Treatment for Patients with Advanced Hepatocellular Carcinoma
Hyung Jun Kwon, Yoon Jin Hwang
Journal of the Korean Liver Cancer Study Group. 2011;11(2):104-110.   Published online September 30, 2011
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Hepatic resection for Hepatocellular carcinoma (HCC) is potentally curative treatment for selected patients. However, the roles of surgical treatment for advanced hepatocellular carcinoma are still uncertain. Although aggressive surgical approach is not recommandable to all patients with advanced HCC, it is clear there is a group of patients that will benefit. In this review article, the authors would like to examine the roles of surgical treatment for patients with advanced hepatocellular carcinoma (HCC) by ascertaining the feasiability and results of surgical resection.
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Case Reports
A Case of Hepatocellular Carcinoma with Early Multiple Recurrences after Liver Resection
Jae Hong Ahn, Hyung Joon Yim, Seung Young Kim, Jeong Han Kim, Yeon Seok Seo, Seung Hwa Lee, Hwan Hoon Chung, Tae Jin Song, Hong Sik Lee, Sang Woo Lee, Soon Ho Um, Jai Hyun Choi, Ho Sang Ryu
Journal of the Korean Liver Cancer Study Group. 2009;9(1):29-32.   Published online June 30, 2009
  • 680 Views
  • 3 Downloads
AbstractAbstract PDF
Hepatic resection is a standard curative therapy for hepatocellular carcinoma (HCC) although only 10~30% of patients are indicated due to advanced stage or poor hepatic reserve. Five year survival rate after resection was reported as a mean of 55% (25~93%), but cases of early recurrence after hepatic resection had poor prognosis. As early recurrence after hepatic resection is the one of the most important factors that determines the prognosis, many investigators have been trying to determine the factors associated with early recurrence. We report a case of early multiple recurrence of HCC after curative hepatic resection probably due to microvascular invasion of tumor and too close resection margin. We would like to suggest that additional prophylactic measures need to be sought in this group of patients because these factors may influence on early recurrence.
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A Case of Massive Hepatocellular Carcinoma Treated by Hepatic Resection, which did not Respond to Transarterial Chemoembolization
Jeong Han Kim, Hyung Joon Yim, Seung Young Kim, Jae Hong Ahn, Ji Hoon Kim, Yeon Seok Seo, Seung Hwa Lee, Hwan Hoon Chung, Tae Jin Song, Hong Sik Lee, Sang Woo Lee, Jai Hyun Choi
Journal of the Korean Liver Cancer Study Group. 2009;9(1):63-66.   Published online June 30, 2009
  • 781 Views
  • 3 Downloads
AbstractAbstract PDF
Surgical resection is the treatment of choice for hepatocellular carcinoma (HCC) in non-cirrhotic patients. The optimal indication for resection is a single tumor in a suitable location for resection. However, limit of the tumor size is not clear. We report a case of successful hepatic resection in patients with massive HCC sized more than 15 cm that did not respond to transarterial chemoembolization (TACE). A 49-year-old male patient had received TACE two times for massive HCC. However, the tumor size increased. Right hemihepatectomy was performed despite the extensive tumor size and underlying liver cirrhosis. Ascites and wound infection were developed after resection, but the patient’s general condition got recovered soon. Until 6 months after surgery, recurrence has not been detected. However, distant metastasis was noted at 7th month. Although recurrence with distant metastasis was noted, we think aggressive surgical approach prolonged this patient’s survival.
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Review Articles
Hepatic Resection Following Adjuvant Treatments in Hepatocellular Carcinoma
Sae-Byeol Choi, Kyung Sik Kim
Journal of the Korean Liver Cancer Study Group. 2008;8(1):32-38.   Published online June 30, 2008
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The optimal treatment of hepatocellular carcinoma has become increasingly complex with myriad of available treatment options. Although recently the liver transplantation has been accepted the best treatment for survival, the shortage of donor limits the extension of this procedures. As the neoadjuvant chemotherapy is being increasingly employed to downsize colorectal metastasis, the clinical trials have been extended to the hepatocellular carcinoma. Therefore we reviewed the use of liver resection following tumor downstaging with chemotherapeutic agents and Radiation therapy to treat unresectable HCC. Key Words: Hepatic resection․Downstaging․Transarterial chemoembolization․Radiation
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Surgical Treatment in Advanced Hepatocellular Carcinoma
Kyung Sik Kim
Journal of the Korean Liver Cancer Study Group. 2006;6(1):1-6.   Published online June 30, 2006
  • 658 Views
  • 2 Downloads
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Hepatic resection has been accepted as one of the most effective treatments for hepatocelluar carcinoma. The various advancements in both operative procedures and perioperative patient management have made the hepatic resection safer and the indications for resection have been also expanded. Recently the International Cooperative Study Group for hepatocellular carcinoma proposed a new staging based on data form multiple centers across the world. According to this new staging, the paradigm of managing advanced hepatocellular carcinoma is being changed. Therefore the experiences on the surgical approach to various situations such as larger HCC above 10 cm in diameter, vascular invasion and lymph node involvement were reviewed.
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Postoperative Early Multinodular Intrahepatic Recurrence of Hepatocellular Carcinoma
Jeong Ho Park, Kwang Cheol Koh
Journal of the Korean Liver Cancer Study Group. 2004;4(1):12-15.   Published online June 30, 2004
  • 638 Views
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