Journal of Liver Cancer

2 "Early recurrence"

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Case Reports

A Case of Hepatocellular Carcinoma with Early Multiple Recurrences after Liver Resection: Jae Hong Ahn, Hyung Joon Yim, Seung Young Kim, Jeong Han Kim, Yeon Seok Seo, Seung Hwa Lee, Hwan Hoon Chung, Tae Jin Song, Hong Sik Lee, Sang Woo Lee, Soon Ho Um, Jai Hyun Choi, Ho Sang Ryu; Journal of the Korean Liver Cancer Study Group. 2009;9(1):29-32. Published online June 30, 2009

Abstract PDF: Hepatic resection is a standard curative therapy for hepatocellular carcinoma (HCC) although only 10~30% of patients are indicated due to advanced stage or poor hepatic reserve. Five year survival rate after resection was reported as a mean of 55% (25~93%), but cases of early recurrence after hepatic resection had poor prognosis. As early recurrence after hepatic resection is the one of the most important factors that determines the prognosis, many investigators have been trying to determine the factors associated with early recurrence. We report a case of early multiple recurrence of HCC after curative hepatic resection probably due to microvascular invasion of tumor and too close resection margin. We would like to suggest that additional prophylactic measures need to be sought in this group of patients because these factors may influence on early recurrence.

Early Extensive Recurrence of Hepatocellular Carcinoma after Non-surgical Treatment: Myoung Kuk Jang, Han Chu Lee, Young-Suk Lim, Young-Hwa Chung, Yung Sang Lee, Dong Jin Suh; Journal of the Korean Liver Cancer Study Group. 2004;4(1):67-72. Published online June 30, 2004

Abstract PDF: Although transarterial chemoembolization (TACE) has been reported to have anti-tumor effects in patients with hepatocellular carcinoma (HCC), optimal time schedules and the appropriate follow-up methods have not been determined yet. We experienced a 57-year-old male who underwent radiofrequency ablation(RFA) therapy due to marginal and viable HCC on CT scan after TACE, despite of negative tumor staining on angiography. The patient did not show any evidence of tumor recurrence on CT scan until five months after RFA, However, follow-up CT scan obtained eight months after RFA showed newly developed a massive recurrent tumor with tumor thrombosis in the right portal vein around the previously treated HCC.

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