Journal of Liver Cancer

Case Reports

A Patient of Hepatocellular Carcinoma Performed Hepatectomy after Tumor Downing Sizing with Transcatheter Arterial Chemoembolization: Seul Ki Min, Sang Gyune Kim, Young Seok Kim, Sae Whan Lee, Soung Won Jeong, Jae Young Jang, Hong Soo Kim, Boo Sung Kim; Journal of the Korean Liver Cancer Study Group. 2011;11(1):40-45. Published online February 28, 2011

Abstract PDF: Hepatocellular carcinoma (HCC) is the third most common cancer in korean population. Surgical management is the mainstay of HCC. Surgical resection and liver transplantation shows the best outcomes in well-selected patients. But few patients are possible to benefit from surgical resection or liver transplantation. The majority of cases of HCC are unresectable, but there are no proven treatment modalities for these cases. In small number of articles showed the favorable result of adjuvant chemotherapy, and transcatheter arterial chemoembolization (TACE) for unresectable HCCs. But there are some drawbacks, such as small number of sample size and variablity of study design at each studies. Hereby we report a patients of HCC, who was performed hepatectomy after tumor down sizing with TACE.

A Case of Multiple Hepatocellular Carcinoma which was Performed Liver Transplantation after Down-staging by Transcatheter Arterial Chemoembolization: Hee-Jung Wang, Bong-Wan Kim, Sung-Won Cho, Je-Hwan Won; Journal of the Korean Liver Cancer Study Group. 2011;11(1):50-55. Published online February 28, 2011

Abstract PDF: A case of multiple hepatocellular carcinoma (HCC) which was performed a living donor liver transplantation (LDLT) after down-staging by transcatheter arterial chemoembolization (TACE) is reviewed. Generally, the recommended therapeutic strategy for this kind of HCC is TACE. However, the response of multiple HCC of this 48 year-old male patient was relatively good after 4 times of TACE, and we performed LDLT on the concept of clinical trial under the informed consent of patient and his families. Although there were two times recurrences in the liver and lung, he has overcome them and is still alive 66 months after LDLT. We suggest that liver transplantation could be an alternative strategy in the multiple HCC cases who show good responses after TACE.

A Case of Hepatocellular Carcinoma with Portal Vein Tumor Thrombi which was Performed Hepatectomy after Down-staging by Proton Therapy: Hee-Jung Wang, Bong-Wan Kim, Wei-Kwang Xu; Journal of the Korean Liver Cancer Study Group. 2011;11(1):56-59. Published online February 28, 2011

Abstract PDF: A case of hepatocellular carcinoma (HCC) with portal vein tumor thrombi (PVTT) which was performed hepatectomy after down-staging by proton therapy is reviewed. Generally, the recommended therapeutic strategy for this kind of HCC is radiation therapy, systemic or infusion anticancer chemotherapy. However, the response of HCC and its PVTT of this 56 year-old male patient was relatively good after 22 times of proton therapy, and we performed right hemihepatectomy on the concept of clinical trial under the informed consent of patient and his families. He is still alive without recurrence 15 months after hepatectomy. We suggest that hemihepatectomy with removal of PVTT could be an alternative strategy in the PVTT accompanied HCC cases who show good responses after the above generally recommended therapies.

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