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Case Report
- A Case of Complete Response by Multidisciplinary Management in a Patient with Solitary Bone Metastasis after Curative Resection of Hepatocellular Carcinoma
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Seawon Hwang, Hyun Yang, Hae Lim Lee, Jeong Won Jang, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon
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J Liver Cancer. 2016;16(1):52-56. Published online March 31, 2016
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DOI: https://doi.org/10.17998/jlc.16.1.52
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Abstract
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- Despite recent advances in the treatment of hepatocellular carcinoma (HCC), the prognosis
of patients with extrahepatic metastasis from HCC still remains dismal. The current study
presents a case of HCC that was metastatic to the pelvis and describes successful treatment
with multidisciplinary approach to the skeletal metastasis. The patient was a 67-year-old
male who presented with right pelvic pain 28 months following right hepatectomy for HCC.
Computed tomography and magnetic resonance imaging indicated a solitary bone metastasis
without intrahepatic recurrence. Complete response was achieved with multidisciplinary
management including sorafenib, transarterial embolization, surgery to remove the
metastatic mass and radiotherapy after surgery. A post-operative follow-up 15 months later
found that the patient remained in good health with maintained complete response. This case
suggests that a multidisciplinary approach can achieve long-term cancer-free survival and
prolonged life expectancy beyond palliative care for patients with solitary bone metastasis
after curative surgery for HCC.
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