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JLC : Journal of Liver Cancer

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4 "Bone metastasis"
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Case Reports
A Case of Hepatocellular Carcinoma Presenting with Rib Metastasis
Kyung In Lee, Young Lan Kwon, Yoon Jung Kim, Hye Jin Seo, Yong Jin Kim, Chang Wook Park, Eun Soo Kim, Byoung Kuk Jang, Woo Jin Chung, Kyung Sik Park, Kwang Bum Cho, Jae Seok Hwang, Jung Hyeok Kwon
Journal of the Korean Liver Cancer Study Group. 2010;10(1):64-68.   Published online June 30, 2010
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AbstractAbstract PDF
Bone metastasis is not uncommon and shows poor survival in patients with hepatocellular carcinoma (HCC). We describe a case of HCC presenting with rib metastasis in a 54-year-old man. In spite of radiotherapy for rib metastasis, pain was sustained and size of lesions were increased. So we performd CT-guided percutaneous ethanol injection therapy (PEIT). Whenever new metastatic bone lesions were detected, we have done PEIT. However, abdominal CT scan at 25th month after diagnosis shows residual viable tumors in pelvic bone and multiple metastatic nodules in both lung. He is alive by taking conservative management for 27 months after diagnosis.
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A case of hepatocellular carcinoma presented with bone metastasis
EJ Kang, SW Jeong, JY Jang, SH Lee, SG Kim, YK Chun, YS Kim, YD Cho, HS Kim, BS Kim
Journal of the Korean Liver Cancer Study Group. 2010;10(1):69-72.   Published online June 30, 2010
  • 746 Views
  • 10 Downloads
AbstractAbstract PDF
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide in terms of incidence. The majority of tumors are diagnosed when advanced. The long-term prognosis of HCC remains poor, with a 5-year survival rate of <5%. However, recent progress in the treatment of HCC has made it possible for the patient to survive longer, and as a result, distant metastasis from HCC, including bone metastasis has increased and attracted more attention than before. Of the various metastatic sites, the most common site is the lungs, followed by the lymph nodes and bone. The most frequent sites of bone metastasis are the spine, pelvis and rib in that order. Single bone lesion was associated with a favorable outcome, while multiple bone lesions may be associated with severe pain and increasing rate of leucopenia, anemia, and thrombocytopenia, sometimes making radiotherapy administration difficult. The incidence of bone metastasis in HCC is low. Moreover HCC diagnosed with bone metastasis is very rare. We report a patient who present with bone metastasis before the diagnosis of a primary cancer.
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A Case of Hepatocellular Carcinoma with Rib Metastasis in a Young Patient in Twenties
Seung Young Kim, Hyung Joon Yim, Jae Hong Ahn, Sung Woo Jung, Jeong Han Kim, Ji Hoon Kim, Ju-Han Lee, Seung Hwa Lee, Hwan Hoon Chung, jong Eun Yeon, Hong Sik Lee, Sang Woo Lee, Kwan Soo Byun, Jai Hyun Choi
Journal of the Korean Liver Cancer Study Group. 2009;9(1):86-89.   Published online June 30, 2009
  • 710 Views
  • 4 Downloads
AbstractAbstract PDF
Helatocellular carcinoma (HCC) is uncommon in young adults, and young HCC patients is known to show poor prognosis than older HCC patients because they have a more advanced tumor stage at diagnosis. We describe a case of HCC in a 28-year old chronic hepatitis B virus carrier who showed multiple nodular HCC with bone metastasis at diagnosis. In spite of multidisciplinary treatment including transarterial chemoembolization (TACE) for liver mass and radiotherapy for metastatic bone lesion, the patient died of cancer progression and weakened general condition 15 months after diagnosis. Therefore, we need to consider periodic surveillance in young chronic hepatitis B virus carriers.
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A Case of Complete Remission after Multiple Sessions of Local Treatment in Metastatic Hepatocellular Carcinoma
Tae Gun Moon, Joon Hyeok Lee, Moon Seok Choi, Kwang Cheol Koh, Jae J. Kim, Seung Woon Paik, Byung Cheol Yoo, Jong Chul Rhee
Journal of the Korean Liver Cancer Study Group. 2006;6(1):70-76.   Published online June 30, 2006
  • 671 Views
  • 3 Downloads
AbstractAbstract PDF
With advances in the diagnosis and local treatement of HCC, which have resulted in a prolongation of survival, extrahepatic metastasis of HCC influence the survival of HCC patients. In particular, the frequency of death due to respiratory failure resulting from pulmonary metastases, pain and fractures resulting from bone metastases has been increased gradually. The efficacy of systemic treatment for the extrahepatic metastases is discouraging because of a lack of effective chemotherapeutic agents, reduced hepatic reserve and adverse effects. We report one
case
of the prolonged survival in a patient with hepatocellular carcinoma after treatment of bone and lung metastases.
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